000 01947 a2200529 4500
005 20250517040115.0
264 0 _c20160520
008 201605s 0 0 eng d
022 _a1464-3405
024 7 _a10.1016/j.bmcl.2015.06.031
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBoucle, Sebastien
245 0 0 _aDesign, synthesis and evaluation of novel anti-HCV molecules that deliver intracellularly three highly potent NS5A inhibitors.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry letters
_cSep 2015
300 _a3711-5 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
650 0 4 _aAnimals
650 0 4 _aAntiviral Agents
_xadministration & dosage
650 0 4 _aCarbamates
650 0 4 _aCell Line
_xdrug effects
650 0 4 _aChemistry Techniques, Synthetic
650 0 4 _aChlorocebus aethiops
650 0 4 _aDrug Design
650 0 4 _aDrug Evaluation, Preclinical
_xmethods
650 0 4 _aHepacivirus
_xdrug effects
650 0 4 _aHumans
650 0 4 _aImidazoles
_xpharmacology
650 0 4 _aMolecular Targeted Therapy
650 0 4 _aMutation
650 0 4 _aPyrrolidines
650 0 4 _aStructure-Activity Relationship
650 0 4 _aValine
_xanalogs & derivatives
650 0 4 _aVero Cells
_xdrug effects
650 0 4 _aViral Nonstructural Proteins
_xantagonists & inhibitors
650 0 4 _aVirus Replication
_xdrug effects
700 1 _aTao, Sijia
700 1 _aAmblard, Franck
700 1 _aStanton, Richard A
700 1 _aNettles, James H
700 1 _aLi, Chengwei
700 1 _aMcBrayer, Tamara R
700 1 _aWhitaker, Tony
700 1 _aCoats, Steven J
700 1 _aSchinazi, Raymond F
773 0 _tBioorganic & medicinal chemistry letters
_gvol. 25
_gno. 17
_gp. 3711-5
856 4 0 _uhttps://doi.org/10.1016/j.bmcl.2015.06.031
_zAvailable from publisher's website
999 _c25006254
_d25006254