000 02064 a2200517 4500
005 20250517034728.0
264 0 _c20151105
008 201511s 0 0 eng d
022 _a1083-351X
024 7 _a10.1074/jbc.M115.651463
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aTomar, Sakshi
245 0 0 _aLigand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro): IMPLICATIONS FOR nsp5 REGULATION AND THE DEVELOPMENT OF ANTIVIRALS.
_h[electronic resource]
260 _bThe Journal of biological chemistry
_cAug 2015
300 _a19403-22 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
650 0 4 _aAmino Acid Sequence
650 0 4 _aAntiviral Agents
_xchemical synthesis
650 0 4 _aCoronavirus 3C Proteases
650 0 4 _aCrystallography, X-Ray
650 0 4 _aCysteine Endopeptidases
_xchemistry
650 0 4 _aEscherichia coli
_xgenetics
650 0 4 _aGene Expression
650 0 4 _aHydrophobic and Hydrophilic Interactions
650 0 4 _aKinetics
650 0 4 _aLigands
650 0 4 _aMiddle East Respiratory Syndrome Coronavirus
_xdrug effects
650 0 4 _aMolecular Docking Simulation
650 0 4 _aMolecular Sequence Data
650 0 4 _aPeptidomimetics
_xchemical synthesis
650 0 4 _aProtein Multimerization
_xdrug effects
650 0 4 _aRecombinant Proteins
_xchemistry
650 0 4 _aSequence Alignment
650 0 4 _aSubstrate Specificity
650 0 4 _aViral Proteins
_xantagonists & inhibitors
700 1 _aJohnston, Melanie L
700 1 _aSt John, Sarah E
700 1 _aOsswald, Heather L
700 1 _aNyalapatla, Prasanth R
700 1 _aPaul, Lake N
700 1 _aGhosh, Arun K
700 1 _aDenison, Mark R
700 1 _aMesecar, Andrew D
773 0 _tThe Journal of biological chemistry
_gvol. 290
_gno. 32
_gp. 19403-22
856 4 0 _uhttps://doi.org/10.1074/jbc.M115.651463
_zAvailable from publisher's website
999 _c24963816
_d24963816