000 02043 a2200589 4500
005 20250517034707.0
264 0 _c20160621
008 201606s 0 0 eng d
022 _a1096-1186
024 7 _a10.1016/j.phrs.2015.05.012
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLi, Yi
245 0 0 _aIlexgenin A inhibits endoplasmic reticulum stress and ameliorates endothelial dysfunction via suppression of TXNIP/NLRP3 inflammasome activation in an AMPK dependent manner.
_h[electronic resource]
260 _bPharmacological research
_cSep 2015
300 _a101-15 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAMP-Activated Protein Kinases
_xdeficiency
650 0 4 _aAnimals
650 0 4 _aAorta, Thoracic
_xdrug effects
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aCardiovascular Diseases
_xdrug therapy
650 0 4 _aCarrier Proteins
_xmetabolism
650 0 4 _aCaspase 3
_xmetabolism
650 0 4 _aCell Line
650 0 4 _aDrugs, Chinese Herbal
_xpharmacology
650 0 4 _aEndoplasmic Reticulum Stress
_xdrug effects
650 0 4 _aEndothelial Cells
_xcytology
650 0 4 _aGene Knockdown Techniques
650 0 4 _aHumans
650 0 4 _aIlex
650 0 4 _aInflammasomes
_xdrug effects
650 0 4 _aLipid Metabolism
_xdrug effects
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Inbred ICR
650 0 4 _aMitochondria
_xdrug effects
650 0 4 _aRats
650 0 4 _aRats, Sprague-Dawley
650 0 4 _aReactive Oxygen Species
_xmetabolism
650 0 4 _aThioredoxins
_xmetabolism
650 0 4 _aTriterpenes
_xpharmacology
700 1 _aYang, Jie
700 1 _aChen, Mei-Hong
700 1 _aWang, Qiang
700 1 _aQin, Min-Jian
700 1 _aZhang, Tong
700 1 _aChen, Xiao-Qing
700 1 _aLiu, Bao-Lin
700 1 _aWen, Xiao-Dong
773 0 _tPharmacological research
_gvol. 99
_gp. 101-15
856 4 0 _uhttps://doi.org/10.1016/j.phrs.2015.05.012
_zAvailable from publisher's website
999 _c24962702
_d24962702