| 000 | 01664 a2200445 4500 | ||
|---|---|---|---|
| 005 | 20250517034545.0 | ||
| 264 | 0 | _c20151013 | |
| 008 | 201510s 0 0 eng d | ||
| 022 | _a1432-0843 | ||
| 024 | 7 |
_a10.1007/s00280-015-2791-y _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aChristner, Susan M | |
| 245 | 0 | 0 |
_aIn vitro cytotoxicity and in vivo efficacy, pharmacokinetics, and metabolism of pyrazole-based small molecule inhibitors of Mdm2/4-p53 interaction. _h[electronic resource] |
| 260 |
_bCancer chemotherapy and pharmacology _cAug 2015 |
||
| 300 |
_a287-99 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 |
_aAntineoplastic Agents _xchemistry |
| 650 | 0 | 4 | _aDrug Screening Assays, Antitumor |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 | _aHCT116 Cells |
| 650 | 0 | 4 | _aHeterografts |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aMice, SCID |
| 650 | 0 | 4 | _aNeoplasm Transplantation |
| 650 | 0 | 4 |
_aProto-Oncogene Proteins _xmetabolism |
| 650 | 0 | 4 |
_aProto-Oncogene Proteins c-mdm2 _xmetabolism |
| 650 | 0 | 4 |
_aPyrazoles _xchemistry |
| 650 | 0 | 4 |
_aTumor Suppressor Protein p53 _xmetabolism |
| 650 | 0 | 4 |
_aUbiquitin-Protein Ligases _xmetabolism |
| 700 | 1 | _aClausen, Dana M | |
| 700 | 1 | _aBeumer, Jan H | |
| 700 | 1 | _aParise, Robert A | |
| 700 | 1 | _aGuo, Jianxia | |
| 700 | 1 | _aHuang, Yijun | |
| 700 | 1 | _aDömling, Alexander S | |
| 700 | 1 | _aEiseman, Julie L | |
| 773 | 0 |
_tCancer chemotherapy and pharmacology _gvol. 76 _gno. 2 _gp. 287-99 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1007/s00280-015-2791-y _zAvailable from publisher's website |
| 999 |
_c24958458 _d24958458 |
||