000 01987 a2200577 4500
005 20250517033433.0
264 0 _c20160226
008 201602s 0 0 eng d
022 _a1464-3391
024 7 _a10.1016/j.bmc.2015.04.062
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aWinneroski, Leonard L
245 0 0 _aPreparation and biological evaluation of conformationally constrained BACE1 inhibitors.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry
_cJul 2015
300 _a3260-8 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
650 0 4 _aAmyloid Precursor Protein Secretases
_xantagonists & inhibitors
650 0 4 _aAnimals
650 0 4 _aAspartic Acid Endopeptidases
_xantagonists & inhibitors
650 0 4 _aBrain Chemistry
650 0 4 _aBridged Bicyclo Compounds
_xchemical synthesis
650 0 4 _aCrystallography, X-Ray
650 0 4 _aDrug Design
650 0 4 _aHumans
650 0 4 _aMice
650 0 4 _aMolecular Conformation
650 0 4 _aMolecular Docking Simulation
650 0 4 _aProtease Inhibitors
_xchemical synthesis
650 0 4 _aStereoisomerism
650 0 4 _aThiazines
_xchemical synthesis
700 1 _aSchiffler, Matthew A
700 1 _aErickson, Jon A
700 1 _aMay, Patrick C
700 1 _aMonk, Scott A
700 1 _aTimm, David E
700 1 _aAudia, James E
700 1 _aBeck, James P
700 1 _aBoggs, Leonard N
700 1 _aBorders, Anthony R
700 1 _aBoyer, Robert D
700 1 _aBrier, Richard A
700 1 _aHudziak, Kevin J
700 1 _aKlimkowski, Valentine J
700 1 _aGarcia Losada, Pablo
700 1 _aMathes, Brian M
700 1 _aStout, Stephanie L
700 1 _aWatson, Brian M
700 1 _aMergott, Dustin J
773 0 _tBioorganic & medicinal chemistry
_gvol. 23
_gno. 13
_gp. 3260-8
856 4 0 _uhttps://doi.org/10.1016/j.bmc.2015.04.062
_zAvailable from publisher's website
999 _c24926906
_d24926906