000 | 01987 a2200577 4500 | ||
---|---|---|---|
005 | 20250517033433.0 | ||
264 | 0 | _c20160226 | |
008 | 201602s 0 0 eng d | ||
022 | _a1464-3391 | ||
024 | 7 |
_a10.1016/j.bmc.2015.04.062 _2doi |
|
040 |
_aNLM _beng _cNLM |
||
100 | 1 | _aWinneroski, Leonard L | |
245 | 0 | 0 |
_aPreparation and biological evaluation of conformationally constrained BACE1 inhibitors. _h[electronic resource] |
260 |
_bBioorganic & medicinal chemistry _cJul 2015 |
||
300 |
_a3260-8 p. _bdigital |
||
500 | _aPublication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. | ||
650 | 0 | 4 |
_aAmyloid Precursor Protein Secretases _xantagonists & inhibitors |
650 | 0 | 4 | _aAnimals |
650 | 0 | 4 |
_aAspartic Acid Endopeptidases _xantagonists & inhibitors |
650 | 0 | 4 | _aBrain Chemistry |
650 | 0 | 4 |
_aBridged Bicyclo Compounds _xchemical synthesis |
650 | 0 | 4 | _aCrystallography, X-Ray |
650 | 0 | 4 | _aDrug Design |
650 | 0 | 4 | _aHumans |
650 | 0 | 4 | _aMice |
650 | 0 | 4 | _aMolecular Conformation |
650 | 0 | 4 | _aMolecular Docking Simulation |
650 | 0 | 4 |
_aProtease Inhibitors _xchemical synthesis |
650 | 0 | 4 | _aStereoisomerism |
650 | 0 | 4 |
_aThiazines _xchemical synthesis |
700 | 1 | _aSchiffler, Matthew A | |
700 | 1 | _aErickson, Jon A | |
700 | 1 | _aMay, Patrick C | |
700 | 1 | _aMonk, Scott A | |
700 | 1 | _aTimm, David E | |
700 | 1 | _aAudia, James E | |
700 | 1 | _aBeck, James P | |
700 | 1 | _aBoggs, Leonard N | |
700 | 1 | _aBorders, Anthony R | |
700 | 1 | _aBoyer, Robert D | |
700 | 1 | _aBrier, Richard A | |
700 | 1 | _aHudziak, Kevin J | |
700 | 1 | _aKlimkowski, Valentine J | |
700 | 1 | _aGarcia Losada, Pablo | |
700 | 1 | _aMathes, Brian M | |
700 | 1 | _aStout, Stephanie L | |
700 | 1 | _aWatson, Brian M | |
700 | 1 | _aMergott, Dustin J | |
773 | 0 |
_tBioorganic & medicinal chemistry _gvol. 23 _gno. 13 _gp. 3260-8 |
|
856 | 4 | 0 |
_uhttps://doi.org/10.1016/j.bmc.2015.04.062 _zAvailable from publisher's website |
999 |
_c24926906 _d24926906 |