| 000 | 01840 a2200481 4500 | ||
|---|---|---|---|
| 005 | 20250517031048.0 | ||
| 264 | 0 | _c20160216 | |
| 008 | 201602s 0 0 eng d | ||
| 022 | _a1521-009X | ||
| 024 | 7 |
_a10.1124/dmd.115.063495 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aSarkar, Ujjal | |
| 245 | 0 | 0 |
_aMetabolite profiling and pharmacokinetic evaluation of hydrocortisone in a perfused three-dimensional human liver bioreactor. _h[electronic resource] |
| 260 |
_bDrug metabolism and disposition: the biological fate of chemicals _cJul 2015 |
||
| 300 |
_a1091-9 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. | ||
| 650 | 0 | 4 | _aBioreactors |
| 650 | 0 | 4 | _aCoculture Techniques |
| 650 | 0 | 4 |
_aCytochrome P-450 CYP3A _xmetabolism |
| 650 | 0 | 4 |
_aCytokines _xbiosynthesis |
| 650 | 0 | 4 |
_aGlucuronides _xmetabolism |
| 650 | 0 | 4 | _aHalf-Life |
| 650 | 0 | 4 |
_aHepatocytes _xmetabolism |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aHydrocortisone _xmetabolism |
| 650 | 0 | 4 |
_aInflammation _xchemically induced |
| 650 | 0 | 4 |
_aInterleukin-5 _xbiosynthesis |
| 650 | 0 | 4 |
_aKupffer Cells _xmetabolism |
| 650 | 0 | 4 |
_aLipopolysaccharides _xpharmacology |
| 650 | 0 | 4 |
_aLiver _xmetabolism |
| 650 | 0 | 4 |
_aTumor Necrosis Factor-alpha _xbiosynthesis |
| 700 | 1 | _aRivera-Burgos, Dinelia | |
| 700 | 1 | _aLarge, Emma M | |
| 700 | 1 | _aHughes, David J | |
| 700 | 1 | _aRavindra, Kodihalli C | |
| 700 | 1 | _aDyer, Rachel L | |
| 700 | 1 | _aEbrahimkhani, Mohammad R | |
| 700 | 1 | _aWishnok, John S | |
| 700 | 1 | _aGriffith, Linda G | |
| 700 | 1 | _aTannenbaum, Steven R | |
| 773 | 0 |
_tDrug metabolism and disposition: the biological fate of chemicals _gvol. 43 _gno. 7 _gp. 1091-9 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1124/dmd.115.063495 _zAvailable from publisher's website |
| 999 |
_c24855051 _d24855051 |
||