| 000 | 02589 a2200805 4500 | ||
|---|---|---|---|
| 005 | 20250517030407.0 | ||
| 264 | 0 | _c20150904 | |
| 008 | 201509s 0 0 eng d | ||
| 022 | _a1520-4804 | ||
| 024 | 7 |
_a10.1021/acs.jmedchem.5b00300 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aShaffer, Christopher L | |
| 245 | 0 | 0 |
_aThe discovery and characterization of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor potentiator N-{(3S,4S)-4-[4-(5-cyano-2-thienyl)phenoxy]tetrahydrofuran-3-yl}propane-2-sulfonamide (PF-04958242). _h[electronic resource] |
| 260 |
_bJournal of medicinal chemistry _cMay 2015 |
||
| 300 |
_a4291-308 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article | ||
| 650 | 0 | 4 | _aAdministration, Oral |
| 650 | 0 | 4 | _aAdolescent |
| 650 | 0 | 4 | _aAdult |
| 650 | 0 | 4 | _aAged |
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 | _aBinding Sites |
| 650 | 0 | 4 | _aDisease Models, Animal |
| 650 | 0 | 4 | _aDogs |
| 650 | 0 | 4 | _aDose-Response Relationship, Drug |
| 650 | 0 | 4 | _aDrug Discovery |
| 650 | 0 | 4 |
_aDrug Evaluation, Preclinical _xmethods |
| 650 | 0 | 4 | _aDrug Stability |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 |
_aMemory, Short-Term _xdrug effects |
| 650 | 0 | 4 | _aMice, Inbred C57BL |
| 650 | 0 | 4 | _aMiddle Aged |
| 650 | 0 | 4 | _aProtein Conformation |
| 650 | 0 | 4 | _aRats, Sprague-Dawley |
| 650 | 0 | 4 |
_aReceptors, AMPA _xmetabolism |
| 650 | 0 | 4 |
_aSchizophrenia _xdrug therapy |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 650 | 0 | 4 |
_aSulfonamides _xchemistry |
| 650 | 0 | 4 |
_aThiophenes _xchemistry |
| 650 | 0 | 4 | _aYoung Adult |
| 700 | 1 | _aPatel, Nandini C | |
| 700 | 1 | _aSchwarz, Jacob | |
| 700 | 1 | _aScialis, Renato J | |
| 700 | 1 | _aWei, Yunjing | |
| 700 | 1 | _aHou, Xinjun J | |
| 700 | 1 | _aXie, Longfei | |
| 700 | 1 | _aKarki, Kapil | |
| 700 | 1 | _aBryce, Dianne K | |
| 700 | 1 | _aOsgood, Sarah M | |
| 700 | 1 | _aHoffmann, William E | |
| 700 | 1 | _aLazzaro, John T | |
| 700 | 1 | _aChang, Cheng | |
| 700 | 1 | _aMcGinnis, Dina F | |
| 700 | 1 | _aLotarski, Susan M | |
| 700 | 1 | _aLiu, JianHua | |
| 700 | 1 | _aObach, R Scott | |
| 700 | 1 | _aWeber, Mark L | |
| 700 | 1 | _aChen, Laigao | |
| 700 | 1 | _aZasadny, Kenneth R | |
| 700 | 1 | _aSeymour, Patricia A | |
| 700 | 1 | _aSchmidt, Christopher J | |
| 700 | 1 | _aHajós, Mihály | |
| 700 | 1 | _aHurst, Raymond S | |
| 700 | 1 | _aPandit, Jayvardhan | |
| 700 | 1 | _aO'Donnell, Christopher J | |
| 773 | 0 |
_tJournal of medicinal chemistry _gvol. 58 _gno. 10 _gp. 4291-308 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1021/acs.jmedchem.5b00300 _zAvailable from publisher's website |
| 999 |
_c24835357 _d24835357 |
||