000 01550 a2200409 4500
005 20250517025815.0
264 0 _c20160108
008 201601s 0 0 eng d
022 _a1471-2407
024 7 _a10.1186/s12885-015-1072-9
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aKümler, Iben
245 0 0 _aA phase II study of weekly irinotecan in patients with locally advanced or metastatic HER2- negative breast cancer and increased copy numbers of the topoisomerase 1 (TOP1) gene: a study protocol.
_h[electronic resource]
260 _bBMC cancer
_cFeb 2015
300 _a78 p.
_bdigital
500 _aPublication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
650 0 4 _aBreast Neoplasms
_xdrug therapy
650 0 4 _aCamptothecin
_xadministration & dosage
650 0 4 _aDNA Topoisomerases, Type I
_xgenetics
650 0 4 _aDrug Administration Schedule
650 0 4 _aFemale
650 0 4 _aGene Dosage
650 0 4 _aGenetic Markers
_xgenetics
650 0 4 _aHumans
650 0 4 _aIrinotecan
650 0 4 _aNeoplasm Metastasis
650 0 4 _aProspective Studies
650 0 4 _aReceptor, ErbB-2
_xgenetics
650 0 4 _aTopoisomerase I Inhibitors
_xadministration & dosage
650 0 4 _aTreatment Outcome
700 1 _aBalslev, Eva
700 1 _aStenvang, Jan
700 1 _aBrünner, Nils
700 1 _aNielsen, Dorte
773 0 _tBMC cancer
_gvol. 15
_gp. 78
856 4 0 _uhttps://doi.org/10.1186/s12885-015-1072-9
_zAvailable from publisher's website
999 _c24816058
_d24816058