000 01845 a2200493 4500
005 20250517025135.0
264 0 _c20160126
008 201601s 0 0 eng d
022 _a1464-3391
024 7 _a10.1016/j.bmc.2015.03.035
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aZhen, Xiao-Li
245 0 0 _aSynthesis and biological evaluation of open-chain analogs of cyclic peptides as inhibitors of cellular Shp2 activity.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry
_cMay 2015
300 _a2562-7 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAcetylcholinesterase
_xchemistry
650 0 4 _aCatalytic Domain
650 0 4 _aCathepsin B
_xantagonists & inhibitors
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aEnzyme Assays
650 0 4 _aEnzyme Inhibitors
_xchemical synthesis
650 0 4 _aGPI-Linked Proteins
_xantagonists & inhibitors
650 0 4 _aGene Expression
650 0 4 _aHeLa Cells
650 0 4 _aHumans
650 0 4 _aIMP Dehydrogenase
_xantagonists & inhibitors
650 0 4 _aKinetics
650 0 4 _aMolecular Docking Simulation
650 0 4 _aPeptides, Cyclic
_xchemical synthesis
650 0 4 _aProteasome Endopeptidase Complex
_xdrug effects
650 0 4 _aProtein Binding
650 0 4 _aProtein Tyrosine Phosphatase, Non-Receptor Type 11
_xantagonists & inhibitors
650 0 4 _aStructure-Activity Relationship
700 1 _aYin, Wen-Hui
700 1 _aTian, Xia
700 1 _aMa, Zhen-Jie
700 1 _aFan, Shi-Ming
700 1 _aHan, Jian-Rong
700 1 _aLiu, Shouxin
773 0 _tBioorganic & medicinal chemistry
_gvol. 23
_gno. 10
_gp. 2562-7
856 4 0 _uhttps://doi.org/10.1016/j.bmc.2015.03.035
_zAvailable from publisher's website
999 _c24796132
_d24796132