000 01884 a2200481 4500
005 20250517025017.0
264 0 _c20160418
008 201604s 0 0 eng d
022 _a1932-6203
024 7 _a10.1371/journal.pone.0124000
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aDas, Laxmidhar
245 0 0 _aLong term effect of curcumin in restoration of tumour suppressor p53 and phase-II antioxidant enzymes via activation of Nrf2 signalling and modulation of inflammation in prevention of cancer.
_h[electronic resource]
260 _bPloS one
_c2015
300 _ae0124000 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAnticarcinogenic Agents
_xpharmacology
650 0 4 _aAntioxidants
_xmetabolism
650 0 4 _aConsensus Sequence
650 0 4 _aCurcumin
_xpharmacology
650 0 4 _aCyclooxygenase 2
_xgenetics
650 0 4 _aGlutathione Reductase
_xgenetics
650 0 4 _aGlutathione Transferase
_xgenetics
650 0 4 _aInflammation Mediators
_xmetabolism
650 0 4 _aLiver
_xdrug effects
650 0 4 _aLymphoma, T-Cell
_xdrug therapy
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Inbred AKR
650 0 4 _aNAD(P)H Dehydrogenase (Quinone)
_xgenetics
650 0 4 _aNF-E2-Related Factor 2
_xgenetics
650 0 4 _aNitric Oxide Synthase Type II
_xgenetics
650 0 4 _aProtein Binding
_xdrug effects
650 0 4 _aRNA, Messenger
_xgenetics
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aTransforming Growth Factor beta1
_xgenetics
650 0 4 _aTumor Microenvironment
_xdrug effects
650 0 4 _aTumor Suppressor Protein p53
_xmetabolism
700 1 _aVinayak, Manjula
773 0 _tPloS one
_gvol. 10
_gno. 4
_gp. e0124000
856 4 0 _uhttps://doi.org/10.1371/journal.pone.0124000
_zAvailable from publisher's website
999 _c24791979
_d24791979