000 01854 a2200493 4500
005 20250517024402.0
264 0 _c20150703
008 201507s 0 0 eng d
022 _a1096-0333
024 7 _a10.1016/j.taap.2015.03.008
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aDoherty, Kimberly R
245 0 0 _aStructural and functional screening in human induced-pluripotent stem cell-derived cardiomyocytes accurately identifies cardiotoxicity of multiple drug types.
_h[electronic resource]
260 _bToxicology and applied pharmacology
_cMay 2015
300 _a51-60 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAntineoplastic Agents
_xclassification
650 0 4 _aBiomarkers
_xmetabolism
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aCells, Cultured
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aHeart Diseases
_xchemically induced
650 0 4 _aHigh-Throughput Screening Assays
650 0 4 _aHumans
650 0 4 _aInduced Pluripotent Stem Cells
_xdrug effects
650 0 4 _aLipid Metabolism
_xdrug effects
650 0 4 _aMolecular Structure
650 0 4 _aMyocytes, Cardiac
_xdrug effects
650 0 4 _aOxidative Stress
_xdrug effects
650 0 4 _aReactive Oxygen Species
_xmetabolism
650 0 4 _aReproducibility of Results
650 0 4 _aRisk Assessment
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTime Factors
650 0 4 _aToxicity Tests
_xmethods
650 0 4 _aTroponin I
_xmetabolism
700 1 _aTalbert, Dominique R
700 1 _aTrusk, Patricia B
700 1 _aMoran, Diarmuid M
700 1 _aShell, Scott A
700 1 _aBacus, Sarah
773 0 _tToxicology and applied pharmacology
_gvol. 285
_gno. 1
_gp. 51-60
856 4 0 _uhttps://doi.org/10.1016/j.taap.2015.03.008
_zAvailable from publisher's website
999 _c24773448
_d24773448