000 01318 a2200373 4500
005 20250517022741.0
264 0 _c20160222
008 201602s 0 0 eng d
022 _a1932-6203
024 7 _a10.1371/journal.pone.0120090
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aTang, Eric D
245 0 0 _aSingle amino acid change in STING leads to constitutive active signaling.
_h[electronic resource]
260 _bPloS one
_c2015
300 _ae0120090 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural
650 0 4 _aAmino Acid Substitution
650 0 4 _aCyclic GMP
_xmetabolism
650 0 4 _aCytosol
_xmetabolism
650 0 4 _aDNA
_xmetabolism
650 0 4 _aHEK293 Cells
650 0 4 _aHumans
650 0 4 _aInterferon Regulatory Factor-3
_xmetabolism
650 0 4 _aMembrane Proteins
_xchemistry
650 0 4 _aMutation, Missense
650 0 4 _aNF-kappa B
_xmetabolism
650 0 4 _aNucleotidyltransferases
_xmetabolism
650 0 4 _aProtein Multimerization
650 0 4 _aProtein Serine-Threonine Kinases
_xmetabolism
650 0 4 _aSignal Transduction
700 1 _aWang, Cun-Yu
773 0 _tPloS one
_gvol. 10
_gno. 3
_gp. e0120090
856 4 0 _uhttps://doi.org/10.1371/journal.pone.0120090
_zAvailable from publisher's website
999 _c24724269
_d24724269