000 01986 a2200517 4500
005 20250517020557.0
264 0 _c20150916
008 201509s 0 0 eng d
022 _a2092-6413
024 7 _a10.1038/emm.2014.127
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aYi, Yong Weon
245 0 0 _aβ-TrCP1 degradation is a novel action mechanism of PI3K/mTOR inhibitors in triple-negative breast cancer cells.
_h[electronic resource]
260 _bExperimental & molecular medicine
_cFeb 2015
300 _ae143 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aCyclin E
_xgenetics
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aFemale
650 0 4 _aFurans
_xpharmacology
650 0 4 _aGene Knockdown Techniques
650 0 4 _aHumans
650 0 4 _aMechanistic Target of Rapamycin Complex 2
650 0 4 _aModels, Biological
650 0 4 _aMultiprotein Complexes
_xantagonists & inhibitors
650 0 4 _aPhosphoinositide-3 Kinase Inhibitors
650 0 4 _aPhosphorylation
_xdrug effects
650 0 4 _aProtein Kinase Inhibitors
_xpharmacology
650 0 4 _aProteolysis
_xdrug effects
650 0 4 _aProto-Oncogene Proteins c-myc
_xgenetics
650 0 4 _aPyridines
_xpharmacology
650 0 4 _aPyrimidines
_xpharmacology
650 0 4 _aTOR Serine-Threonine Kinases
_xantagonists & inhibitors
650 0 4 _aTriple Negative Breast Neoplasms
_xgenetics
650 0 4 _abeta-Transducin Repeat-Containing Proteins
_xgenetics
700 1 _aKang, Hyo Jin
700 1 _aBae, Edward Jeong
700 1 _aOh, Seunghoon
700 1 _aSeong, Yeon-Sun
700 1 _aBae, Insoo
773 0 _tExperimental & molecular medicine
_gvol. 47
_gp. e143
856 4 0 _uhttps://doi.org/10.1038/emm.2014.127
_zAvailable from publisher's website
999 _c24659830
_d24659830