000 02245 a2200649 4500
005 20250517014411.0
264 0 _c20160123
008 201601s 0 0 eng d
022 _a1538-7445
024 7 _a10.1158/0008-5472.CAN-14-1589
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aJiang, Feng
245 0 0 _aCYP3A5 Functions as a Tumor Suppressor in Hepatocellular Carcinoma by Regulating mTORC2/Akt Signaling.
_h[electronic resource]
260 _bCancer research
_cApr 2015
300 _a1470-81 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aCarcinoma, Hepatocellular
_xenzymology
650 0 4 _aCell Movement
650 0 4 _aCytochrome P-450 CYP3A
_xphysiology
650 0 4 _aDown-Regulation
650 0 4 _aGene Expression Regulation, Neoplastic
650 0 4 _aGenes, Tumor Suppressor
650 0 4 _aHumans
650 0 4 _aKaplan-Meier Estimate
650 0 4 _aLiver Neoplasms
_xenzymology
650 0 4 _aLung Neoplasms
_xenzymology
650 0 4 _aMechanistic Target of Rapamycin Complex 2
650 0 4 _aMice, Nude
650 0 4 _aMultiprotein Complexes
_xmetabolism
650 0 4 _aNeoplasm Invasiveness
650 0 4 _aNeoplasm Transplantation
650 0 4 _aPrognosis
650 0 4 _aProportional Hazards Models
650 0 4 _aProtein Processing, Post-Translational
650 0 4 _aProto-Oncogene Proteins c-akt
_xmetabolism
650 0 4 _aSignal Transduction
650 0 4 _aTOR Serine-Threonine Kinases
_xmetabolism
650 0 4 _aTissue Inhibitor of Metalloproteinase-1
_xgenetics
650 0 4 _aTissue Inhibitor of Metalloproteinase-2
_xgenetics
650 0 4 _aTranscriptional Activation
700 1 _aChen, Lei
700 1 _aYang, Ying-Cheng
700 1 _aWang, Xian-Ming
700 1 _aWang, Ruo-Yu
700 1 _aLi, Liang
700 1 _aWen, Wen
700 1 _aChang, Yan-Xin
700 1 _aChen, Cai-Yang
700 1 _aTang, Jing
700 1 _aLiu, Gao-Mi-Yang
700 1 _aHuang, Wen-Tao
700 1 _aXu, Lin
700 1 _aWang, Hong-Yang
773 0 _tCancer research
_gvol. 75
_gno. 7
_gp. 1470-81
856 4 0 _uhttps://doi.org/10.1158/0008-5472.CAN-14-1589
_zAvailable from publisher's website
999 _c24592701
_d24592701