000 02156 a2200565 4500
005 20250517013259.0
264 0 _c20150804
008 201508s 0 0 eng d
022 _a1349-7006
024 7 _a10.1111/cas.12616
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSagawa, Morihiko
245 0 0 _aTM-233, a novel analog of 1'-acetoxychavicol acetate, induces cell death in myeloma cells by inhibiting both JAK/STAT and proteasome activities.
_h[electronic resource]
260 _bCancer science
_cApr 2015
300 _a438-46 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aBenzyl Alcohols
_xchemistry
650 0 4 _aBoronic Acids
_xpharmacology
650 0 4 _aBortezomib
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aDrug Resistance, Neoplasm
_xdrug effects
650 0 4 _aG1 Phase Cell Cycle Checkpoints
_xdrug effects
650 0 4 _aHumans
650 0 4 _aJanus Kinase 2
_xantagonists & inhibitors
650 0 4 _aMultiple Myeloma
_xenzymology
650 0 4 _aMyeloid Cell Leukemia Sequence 1 Protein
_xbiosynthesis
650 0 4 _aNF-kappa B
_xantagonists & inhibitors
650 0 4 _aProteasome Endopeptidase Complex
_xmetabolism
650 0 4 _aProteasome Inhibitors
_xpharmacology
650 0 4 _aProto-Oncogene Proteins c-bcl-2
_xbiosynthesis
650 0 4 _aPyrazines
_xpharmacology
650 0 4 _aQuantitative Structure-Activity Relationship
650 0 4 _aSTAT3 Transcription Factor
_xantagonists & inhibitors
650 0 4 _abcl-X Protein
_xbiosynthesis
700 1 _aTabayashi, Takayuki
700 1 _aKimura, Yuta
700 1 _aTomikawa, Tatsuki
700 1 _aNemoto-Anan, Tomoe
700 1 _aWatanabe, Reiko
700 1 _aTokuhira, Michihide
700 1 _aRi, Masaki
700 1 _aHashimoto, Yuichi
700 1 _aIida, Shinsuke
700 1 _aKizaki, Masahiro
773 0 _tCancer science
_gvol. 106
_gno. 4
_gp. 438-46
856 4 0 _uhttps://doi.org/10.1111/cas.12616
_zAvailable from publisher's website
999 _c24557940
_d24557940