| 000 | 02593 a2200793 4500 | ||
|---|---|---|---|
| 005 | 20250517013147.0 | ||
| 264 | 0 | _c20160519 | |
| 008 | 201605s 0 0 eng d | ||
| 022 | _a1569-8041 | ||
| 024 | 7 |
_a10.1093/annonc/mdv026 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aWong, A L | |
| 245 | 0 | 0 |
_aPhase I and biomarker study of OPB-51602, a novel signal transducer and activator of transcription (STAT) 3 inhibitor, in patients with refractory solid malignancies. _h[electronic resource] |
| 260 |
_bAnnals of oncology : official journal of the European Society for Medical Oncology _cMay 2015 |
||
| 300 |
_a998-1005 p. _bdigital |
||
| 500 | _aPublication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAdministration, Oral |
| 650 | 0 | 4 | _aAdult |
| 650 | 0 | 4 | _aAged |
| 650 | 0 | 4 | _aAged, 80 and over |
| 650 | 0 | 4 |
_aAntineoplastic Agents _xadministration & dosage |
| 650 | 0 | 4 | _aAsia |
| 650 | 0 | 4 |
_aBiomarkers, Tumor _xantagonists & inhibitors |
| 650 | 0 | 4 | _aBiotransformation |
| 650 | 0 | 4 |
_aCarcinoma, Non-Small-Cell Lung _xblood |
| 650 | 0 | 4 | _aDose-Response Relationship, Drug |
| 650 | 0 | 4 | _aDrug Administration Schedule |
| 650 | 0 | 4 |
_aErbB Receptors _xgenetics |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 | _aHalf-Life |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aLung Neoplasms _xblood |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 | _aMaximum Tolerated Dose |
| 650 | 0 | 4 | _aMetabolic Clearance Rate |
| 650 | 0 | 4 | _aMiddle Aged |
| 650 | 0 | 4 | _aMolecular Targeted Therapy |
| 650 | 0 | 4 | _aMutation |
| 650 | 0 | 4 | _aPhosphorylation |
| 650 | 0 | 4 |
_aSTAT3 Transcription Factor _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aSignal Transduction _xdrug effects |
| 650 | 0 | 4 | _aTreatment Outcome |
| 700 | 1 | _aSoo, R A | |
| 700 | 1 | _aTan, D S | |
| 700 | 1 | _aLee, S C | |
| 700 | 1 | _aLim, J S | |
| 700 | 1 | _aMarban, P C | |
| 700 | 1 | _aKong, L R | |
| 700 | 1 | _aLee, Y J | |
| 700 | 1 | _aWang, L Z | |
| 700 | 1 | _aThuya, W L | |
| 700 | 1 | _aSoong, R | |
| 700 | 1 | _aYee, M Q | |
| 700 | 1 | _aChin, T M | |
| 700 | 1 | _aCordero, M T | |
| 700 | 1 | _aAsuncion, B R | |
| 700 | 1 | _aPang, B | |
| 700 | 1 | _aPervaiz, S | |
| 700 | 1 | _aHirpara, J L | |
| 700 | 1 | _aSinha, A | |
| 700 | 1 | _aXu, W W | |
| 700 | 1 | _aYuasa, M | |
| 700 | 1 | _aTsunoda, T | |
| 700 | 1 | _aMotoyama, M | |
| 700 | 1 | _aYamauchi, T | |
| 700 | 1 | _aGoh, B C | |
| 773 | 0 |
_tAnnals of oncology : official journal of the European Society for Medical Oncology _gvol. 26 _gno. 5 _gp. 998-1005 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1093/annonc/mdv026 _zAvailable from publisher's website |
| 999 |
_c24553763 _d24553763 |
||