000 02164 a2200577 4500
005 20250517011512.0
264 0 _c20160119
008 201601s 0 0 eng d
022 _a1573-0646
024 7 _a10.1007/s10637-014-0199-x
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aPetrylak, Daniel P
245 0 0 _aPhase 1/2 study of orteronel (TAK-700), an investigational 17,20-lyase inhibitor, with docetaxel-prednisone in metastatic castration-resistant prostate cancer.
_h[electronic resource]
260 _bInvestigational new drugs
_cApr 2015
300 _a397-408 p.
_bdigital
500 _aPublication Type: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
650 0 4 _aAged
650 0 4 _aAged, 80 and over
650 0 4 _aAntineoplastic Agents
_xadministration & dosage
650 0 4 _aAntineoplastic Combined Chemotherapy Protocols
650 0 4 _aDehydroepiandrosterone Sulfate
_xblood
650 0 4 _aDisease Progression
650 0 4 _aDisease-Free Survival
650 0 4 _aDocetaxel
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aHumans
650 0 4 _aImidazoles
_xadministration & dosage
650 0 4 _aMale
650 0 4 _aMiddle Aged
650 0 4 _aNaphthalenes
_xadministration & dosage
650 0 4 _aPrednisone
_xadministration & dosage
650 0 4 _aProstate-Specific Antigen
650 0 4 _aProstatic Neoplasms, Castration-Resistant
_xdrug therapy
650 0 4 _aSteroid 17-alpha-Hydroxylase
_xantagonists & inhibitors
650 0 4 _aTaxoids
_xadministration & dosage
650 0 4 _aTestosterone
_xblood
700 1 _aGandhi, Jitendra G
700 1 _aClark, William R
700 1 _aHeath, Elisabeth
700 1 _aLin, Jianqing
700 1 _aOh, William K
700 1 _aAgus, David B
700 1 _aCarthon, Bradley
700 1 _aMoran, Susan
700 1 _aKong, Ning
700 1 _aSuri, Ajit
700 1 _aBargfrede, Michael
700 1 _aLiu, Glenn
773 0 _tInvestigational new drugs
_gvol. 33
_gno. 2
_gp. 397-408
856 4 0 _uhttps://doi.org/10.1007/s10637-014-0199-x
_zAvailable from publisher's website
999 _c24503561
_d24503561