000 01409 a2200373 4500
005 20250517011205.0
264 0 _c20151203
008 201512s 0 0 eng d
022 _a1520-6017
024 7 _a10.1002/jps.24293
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBudyak, Ivan L
245 0 0 _aTechnical decision-making with higher order structure data: specific binding of a nonionic detergent perturbs higher order structure of a therapeutic monoclonal antibody.
_h[electronic resource]
260 _bJournal of pharmaceutical sciences
_cApr 2015
300 _a1543-7 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aAntibodies, Monoclonal
_xchemistry
650 0 4 _aBiological Products
_xchemistry
650 0 4 _aChemistry, Pharmaceutical
650 0 4 _aDecision Support Techniques
650 0 4 _aDetergents
_xchemistry
650 0 4 _aDrug Discovery
_xmethods
650 0 4 _aDrug Stability
650 0 4 _aOctoxynol
_xchemistry
650 0 4 _aProtein Conformation
650 0 4 _aProtein Stability
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTechnology, Pharmaceutical
_xmethods
650 0 4 _aTemperature
700 1 _aDoyle, Brandon L
700 1 _aWeiss, William F
773 0 _tJournal of pharmaceutical sciences
_gvol. 104
_gno. 4
_gp. 1543-7
856 4 0 _uhttps://doi.org/10.1002/jps.24293
_zAvailable from publisher's website
999 _c24493380
_d24493380