000 01640 a2200457 4500
005 20250517010529.0
264 0 _c20150115
008 201501s 0 0 eng d
022 _a1095-9203
024 7 _a10.1126/science.1253799
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aFunato, Kosuke
245 0 0 _aUse of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation.
_h[electronic resource]
260 _bScience (New York, N.Y.)
_cDec 2014
300 _a1529-33 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aBrain Stem Neoplasms
_xgenetics
650 0 4 _aCell Transformation, Neoplastic
_xgenetics
650 0 4 _aChild
650 0 4 _aDrug Screening Assays, Antitumor
650 0 4 _aEmbryonic Stem Cells
_xmetabolism
650 0 4 _aEpigenesis, Genetic
650 0 4 _aGene Expression Regulation, Neoplastic
650 0 4 _aGenome-Wide Association Study
650 0 4 _aGlioma
_xgenetics
650 0 4 _aHistones
_xgenetics
650 0 4 _aHumans
650 0 4 _aMice
650 0 4 _aModels, Genetic
650 0 4 _aNeural Stem Cells
_xmetabolism
650 0 4 _aProto-Oncogene Proteins
_xantagonists & inhibitors
650 0 4 _aTumor Suppressor Protein p53
_xgenetics
700 1 _aMajor, Tamara
700 1 _aLewis, Peter W
700 1 _aAllis, C David
700 1 _aTabar, Viviane
773 0 _tScience (New York, N.Y.)
_gvol. 346
_gno. 6216
_gp. 1529-33
856 4 0 _uhttps://doi.org/10.1126/science.1253799
_zAvailable from publisher's website
999 _c24473735
_d24473735