000			02306 a2200565 4500
005			20250517005827.0
264		0	_c20151026
008			201510s 0 0 eng d
022			_a1879-0712
024	7		_a10.1016/j.ejphar.2014.11.040 _2doi
040			_aNLM _beng _cNLM
100	1		_aLi, Ao
245	0	0	_aThe inhibition of activated hepatic stellate cells proliferation by arctigenin through G0/G1 phase cell cycle arrest: persistent p27(Kip1) induction by interfering with PI3K/Akt/FOXO3a signaling pathway. _h[electronic resource]
260			_bEuropean journal of pharmacology _cJan 2015
300			_a71-87 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_a14-3-3 Proteins _xmetabolism
650	0	4	_aActive Transport, Cell Nucleus _xdrug effects
650	0	4	_aBecaplermin
650	0	4	_aCell Line
650	0	4	_aCell Nucleus _xdrug effects
650	0	4	_aCell Proliferation _xdrug effects
650	0	4	_aCyclin D1 _xmetabolism
650	0	4	_aCyclin-Dependent Kinase 4 _xmetabolism
650	0	4	_aCyclin-Dependent Kinase 6 _xmetabolism
650	0	4	_aCyclin-Dependent Kinase Inhibitor p27 _xmetabolism
650	0	4	_aDown-Regulation _xdrug effects
650	0	4	_aForkhead Box Protein O3
650	0	4	_aForkhead Transcription Factors _xdeficiency
650	0	4	_aFurans _xpharmacology
650	0	4	_aG1 Phase Cell Cycle Checkpoints _xdrug effects
650	0	4	_aGene Expression Regulation, Enzymologic _xdrug effects
650	0	4	_aGene Knockdown Techniques
650	0	4	_aHepatic Stellate Cells _xcytology
650	0	4	_aHumans
650	0	4	_aLignans _xpharmacology
650	0	4	_aPhosphatidylinositol 3-Kinases _xmetabolism
650	0	4	_aPhosphorylation _xdrug effects
650	0	4	_aProto-Oncogene Proteins c-akt _xmetabolism
650	0	4	_aProto-Oncogene Proteins c-sis _xpharmacology
650	0	4	_aRNA, Small Interfering _xgenetics
650	0	4	_aResting Phase, Cell Cycle _xdrug effects
650	0	4	_aSignal Transduction _xdrug effects
700	1		_aWang, Jun
700	1		_aWu, Mingjun
700	1		_aZhang, Xiaoxun
700	1		_aZhang, Hongzhi
773	0		_tEuropean journal of pharmacology _gvol. 747 _gp. 71-87
856	4	0	_uhttps://doi.org/10.1016/j.ejphar.2014.11.040 _zAvailable from publisher's website
999			_c24451117 _d24451117