000 01559 a2200421 4500
005 20250517005719.0
264 0 _c20151022
008 201510s 0 0 eng d
022 _a1464-3391
024 7 _a10.1016/j.bmc.2014.11.029
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aZhao, Meng-Yue
245 0 0 _aSynthesis, biological evaluation and 3D-QSAR study of novel 4,5-dihydro-1H-pyrazole thiazole derivatives as BRAF(V⁶⁰⁰E) inhibitors.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry
_cJan 2015
300 _a46-54 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aHumans
650 0 4 _aMCF-7 Cells
650 0 4 _aMolecular Docking Simulation
650 0 4 _aProtein Kinase Inhibitors
_xchemical synthesis
650 0 4 _aProto-Oncogene Proteins B-raf
_xantagonists & inhibitors
650 0 4 _aPyrazoles
_xchemical synthesis
650 0 4 _aQuantitative Structure-Activity Relationship
650 0 4 _aThiazoles
_xchemical synthesis
700 1 _aYin, Yong
700 1 _aYu, Xiao-Wei
700 1 _aSangani, Chetan B
700 1 _aWang, Shu-Fu
700 1 _aLu, Ai-Min
700 1 _aYang, Li-Fang
700 1 _aLv, Peng-Cheng
700 1 _aJiang, Ming-Guo
700 1 _aZhu, Hai-Liang
773 0 _tBioorganic & medicinal chemistry
_gvol. 23
_gno. 1
_gp. 46-54
856 4 0 _uhttps://doi.org/10.1016/j.bmc.2014.11.029
_zAvailable from publisher's website
999 _c24449177
_d24449177