000 01970 a2200529 4500
005 20250517005215.0
264 0 _c20150921
008 201509s 0 0 eng d
022 _a1464-3405
024 7 _a10.1016/j.bmcl.2014.09.070
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aIvanenkov, Yan A
245 0 0 _aDesign, synthesis and biological evaluation of novel potent MDM2/p53 small-molecule inhibitors.
_h[electronic resource]
260 _bBioorganic & medicinal chemistry letters
_cJan 2015
300 _a404-9 p.
_bdigital
500 _aPublication Type: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAntineoplastic Agents
_xchemical synthesis
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aDrug Design
650 0 4 _aHumans
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Dynamics Simulation
650 0 4 _aMolecular Structure
650 0 4 _aNeoplasms
_xdrug therapy
650 0 4 _aProto-Oncogene Proteins c-mdm2
_xantagonists & inhibitors
650 0 4 _aSmall Molecule Libraries
_xchemical synthesis
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTumor Cells, Cultured
650 0 4 _aTumor Suppressor Protein p53
_xantagonists & inhibitors
700 1 _aVasilevski, Sergei V
700 1 _aBeloglazkina, Elena K
700 1 _aKukushkin, Maksim E
700 1 _aMachulkin, Alexey E
700 1 _aVeselov, Mark S
700 1 _aChufarova, Nina V
700 1 _aChernyaginab, Elizaveta S
700 1 _aVanzcool, Anton S
700 1 _aZyk, Nikolay V
700 1 _aSkvortsov, Dmitry A
700 1 _aKhutornenko, Anastasia A
700 1 _aRusanov, Alexander L
700 1 _aTonevitsky, Alexander G
700 1 _aDontsova, Olga A
700 1 _aMajouga, Alexander G
773 0 _tBioorganic & medicinal chemistry letters
_gvol. 25
_gno. 2
_gp. 404-9
856 4 0 _uhttps://doi.org/10.1016/j.bmcl.2014.09.070
_zAvailable from publisher's website
999 _c24432866
_d24432866