000 01809 a2200529 4500
005 20250517005124.0
264 0 _c20160119
008 201601s 0 0 eng d
022 _a1573-0646
024 7 _a10.1007/s10637-014-0190-6
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aPan, Yong
245 0 0 _aPBI-05204, a supercritical CO₂ extract of Nerium oleander, inhibits growth of human pancreatic cancer via targeting the PI3K/mTOR pathway.
_h[electronic resource]
260 _bInvestigational new drugs
_cApr 2015
300 _a271-9 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural
650 0 4 _aAnimals
650 0 4 _aCardiac Glycosides
_xpharmacology
650 0 4 _aCell Cycle
650 0 4 _aCell Line, Tumor
650 0 4 _aClass Ib Phosphatidylinositol 3-Kinase
_xbiosynthesis
650 0 4 _aDeoxycytidine
_xanalogs & derivatives
650 0 4 _aDown-Regulation
650 0 4 _aFemale
650 0 4 _aHumans
650 0 4 _aMice
650 0 4 _aMice, Inbred BALB C
650 0 4 _aNerium
650 0 4 _aPancreatic Neoplasms
_xdrug therapy
650 0 4 _aPlant Extracts
_xpharmacology
650 0 4 _aProto-Oncogene Proteins c-akt
_xbiosynthesis
650 0 4 _aTOR Serine-Threonine Kinases
_xbiosynthesis
650 0 4 _aGemcitabine
700 1 _aRhea, Patrea
700 1 _aTan, Lin
700 1 _aCartwright, Carrie
700 1 _aLee, Ho-Jeong
700 1 _aRavoori, Murali K
700 1 _aAddington, Crandell
700 1 _aGagea, Mihai
700 1 _aKundra, Vikas
700 1 _aKim, Sun-Jin
700 1 _aNewman, Robert A
700 1 _aYang, Peiying
773 0 _tInvestigational new drugs
_gvol. 33
_gno. 2
_gp. 271-9
856 4 0 _uhttps://doi.org/10.1007/s10637-014-0190-6
_zAvailable from publisher's website
999 _c24430146
_d24430146