000 02061 a2200565 4500
005 20250517004253.0
264 0 _c20160314
008 201603s 0 0 eng d
022 _a1552-4604
024 7 _a10.1002/jcph.437
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aSuttle, A Benjamin
245 0 0 _aAssessment of the drug interaction potential and single- and repeat-dose pharmacokinetics of the BRAF inhibitor dabrafenib.
_h[electronic resource]
260 _bJournal of clinical pharmacology
_cApr 2015
300 _a392-400 p.
_bdigital
500 _aPublication Type: Controlled Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
650 0 4 _aAnticoagulants
_xpharmacokinetics
650 0 4 _aCytochrome P-450 CYP2C8 Inhibitors
_xpharmacology
650 0 4 _aCytochrome P-450 CYP3A Inhibitors
_xpharmacology
650 0 4 _aDrug Interactions
650 0 4 _aFemale
650 0 4 _aGemfibrozil
_xpharmacology
650 0 4 _aHumans
650 0 4 _aImidazoles
_xadministration & dosage
650 0 4 _aKetoconazole
_xpharmacology
650 0 4 _aMale
650 0 4 _aMiddle Aged
650 0 4 _aOximes
_xadministration & dosage
650 0 4 _aProtein Kinase Inhibitors
_xadministration & dosage
650 0 4 _aProto-Oncogene Proteins B-raf
_xantagonists & inhibitors
650 0 4 _aWarfarin
_xpharmacokinetics
700 1 _aGrossmann, Kenneth F
700 1 _aOuellet, Daniele
700 1 _aRichards-Peterson, Lauren E
700 1 _aAktan, Gursel
700 1 _aGordon, Michael S
700 1 _aLoRusso, Patricia M
700 1 _aInfante, Jeffrey R
700 1 _aSharma, Sunil
700 1 _aKendra, Kari
700 1 _aPatel, Manish
700 1 _aPant, Shubham
700 1 _aArkenau, Hendrik-Tobias
700 1 _aMiddleton, Mark R
700 1 _aBlackman, Samuel C
700 1 _aBotbyl, Jeff
700 1 _aCarson, Stanley W
773 0 _tJournal of clinical pharmacology
_gvol. 55
_gno. 4
_gp. 392-400
856 4 0 _uhttps://doi.org/10.1002/jcph.437
_zAvailable from publisher's website
999 _c24404218
_d24404218