000 01769 a2200481 4500
005 20250517004235.0
264 0 _c20170904
008 201709s 0 0 eng d
022 _a1096-0333
024 7 _a10.1016/j.taap.2014.10.002
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aWu, Xue-Feng
245 0 0 _aSuppression of NF-κB signaling and NLRP3 inflammasome activation in macrophages is responsible for the amelioration of experimental murine colitis by the natural compound fraxinellone.
_h[electronic resource]
260 _bToxicology and applied pharmacology
_c11 2014
300 _a146-56 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAnimals
650 0 4 _aBenzofurans
_xpharmacology
650 0 4 _aCell Line
650 0 4 _aColitis
_xchemically induced
650 0 4 _aDextran Sulfate
_xtoxicity
650 0 4 _aDisease Models, Animal
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aHumans
650 0 4 _aInflammasomes
_xantagonists & inhibitors
650 0 4 _aMacrophages, Peritoneal
_xdrug effects
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Inbred C57BL
650 0 4 _aNF-kappa B
_xantagonists & inhibitors
650 0 4 _aNLR Family, Pyrin Domain-Containing 3 Protein
_xantagonists & inhibitors
650 0 4 _aSignal Transduction
_xdrug effects
700 1 _aOuyang, Zi-Jun
700 1 _aFeng, Li-Li
700 1 _aChen, Gong
700 1 _aGuo, Wen-Jie
700 1 _aShen, Yan
700 1 _aWu, Xu-Dong
700 1 _aSun, Yang
700 1 _aXu, Qiang
773 0 _tToxicology and applied pharmacology
_gvol. 281
_gno. 1
_gp. 146-56
856 4 0 _uhttps://doi.org/10.1016/j.taap.2014.10.002
_zAvailable from publisher's website
999 _c24403253
_d24403253