| 000 | 02783 a2200817 4500 | ||
|---|---|---|---|
| 005 | 20250517002725.0 | ||
| 264 | 0 | _c20150107 | |
| 008 | 201501s 0 0 eng d | ||
| 022 | _a1533-4406 | ||
| 024 | 7 |
_a10.1056/NEJMoa1412690 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aRobert, Caroline | |
| 245 | 0 | 0 |
_aImproved overall survival in melanoma with combined dabrafenib and trametinib. _h[electronic resource] |
| 260 |
_bThe New England journal of medicine _cJan 2015 |
||
| 300 |
_a30-9 p. _bdigital |
||
| 500 | _aPublication Type: Clinical Trial, Phase III; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAdolescent |
| 650 | 0 | 4 | _aAdult |
| 650 | 0 | 4 | _aAged |
| 650 | 0 | 4 | _aAged, 80 and over |
| 650 | 0 | 4 |
_aAntineoplastic Combined Chemotherapy Protocols _xadverse effects |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aImidazoles _xadministration & dosage |
| 650 | 0 | 4 |
_aIndoles _xadverse effects |
| 650 | 0 | 4 | _aIntention to Treat Analysis |
| 650 | 0 | 4 | _aKaplan-Meier Estimate |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 |
_aMelanoma _xdrug therapy |
| 650 | 0 | 4 | _aMiddle Aged |
| 650 | 0 | 4 |
_aMitogen-Activated Protein Kinase Kinases _xantagonists & inhibitors |
| 650 | 0 | 4 | _aMutation |
| 650 | 0 | 4 |
_aOximes _xadministration & dosage |
| 650 | 0 | 4 |
_aProtein Kinase Inhibitors _xadministration & dosage |
| 650 | 0 | 4 |
_aProto-Oncogene Proteins B-raf _xantagonists & inhibitors |
| 650 | 0 | 4 |
_aPyridones _xadministration & dosage |
| 650 | 0 | 4 |
_aPyrimidinones _xadministration & dosage |
| 650 | 0 | 4 |
_aSkin Neoplasms _xdrug therapy |
| 650 | 0 | 4 |
_aSulfonamides _xadverse effects |
| 650 | 0 | 4 | _aSurvival Analysis |
| 650 | 0 | 4 | _aVemurafenib |
| 650 | 0 | 4 | _aYoung Adult |
| 700 | 1 | _aKaraszewska, Boguslawa | |
| 700 | 1 | _aSchachter, Jacob | |
| 700 | 1 | _aRutkowski, Piotr | |
| 700 | 1 | _aMackiewicz, Andrzej | |
| 700 | 1 | _aStroiakovski, Daniil | |
| 700 | 1 | _aLichinitser, Michael | |
| 700 | 1 | _aDummer, Reinhard | |
| 700 | 1 | _aGrange, Florent | |
| 700 | 1 | _aMortier, Laurent | |
| 700 | 1 | _aChiarion-Sileni, Vanna | |
| 700 | 1 | _aDrucis, Kamil | |
| 700 | 1 | _aKrajsova, Ivana | |
| 700 | 1 | _aHauschild, Axel | |
| 700 | 1 | _aLorigan, Paul | |
| 700 | 1 | _aWolter, Pascal | |
| 700 | 1 | _aLong, Georgina V | |
| 700 | 1 | _aFlaherty, Keith | |
| 700 | 1 | _aNathan, Paul | |
| 700 | 1 | _aRibas, Antoni | |
| 700 | 1 | _aMartin, Anne-Marie | |
| 700 | 1 | _aSun, Peng | |
| 700 | 1 | _aCrist, Wendy | |
| 700 | 1 | _aLegos, Jeff | |
| 700 | 1 | _aRubin, Stephen D | |
| 700 | 1 | _aLittle, Shonda M | |
| 700 | 1 | _aSchadendorf, Dirk | |
| 773 | 0 |
_tThe New England journal of medicine _gvol. 372 _gno. 1 _gp. 30-9 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1056/NEJMoa1412690 _zAvailable from publisher's website |
| 999 |
_c24356209 _d24356209 |
||