| 000 | 01605 a2200457 4500 | ||
|---|---|---|---|
| 005 | 20250517002610.0 | ||
| 264 | 0 | _c20151019 | |
| 008 | 201510s 0 0 eng d | ||
| 022 | _a0948-5023 | ||
| 024 | 7 |
_a10.1007/s00894-014-2515-y _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aLi, Aibo | |
| 245 | 0 | 0 |
_aDiscovery of novel covalent proteasome inhibitors through a combination of pharmacophore screening, covalent docking, and molecular dynamics simulations. _h[electronic resource] |
| 260 |
_bJournal of molecular modeling _cNov 2014 |
||
| 300 |
_a2515 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 | _aBinding Sites |
| 650 | 0 | 4 | _aDatabases, Chemical |
| 650 | 0 | 4 | _aDatabases, Pharmaceutical |
| 650 | 0 | 4 |
_aDrug Discovery _xmethods |
| 650 | 0 | 4 | _aLigands |
| 650 | 0 | 4 | _aMice |
| 650 | 0 | 4 | _aMolecular Docking Simulation |
| 650 | 0 | 4 | _aMolecular Dynamics Simulation |
| 650 | 0 | 4 | _aMolecular Structure |
| 650 | 0 | 4 | _aMolecular Targeted Therapy |
| 650 | 0 | 4 |
_aProteasome Endopeptidase Complex _xchemistry |
| 650 | 0 | 4 |
_aProteasome Inhibitors _xchemistry |
| 650 | 0 | 4 | _aProtein Binding |
| 650 | 0 | 4 | _aProtein Conformation |
| 650 | 0 | 4 | _aStructure-Activity Relationship |
| 700 | 1 | _aSun, Haopeng | |
| 700 | 1 | _aDu, Lei | |
| 700 | 1 | _aWu, Xiaoxin | |
| 700 | 1 | _aCao, Jianqin | |
| 700 | 1 | _aYou, Qidong | |
| 700 | 1 | _aLi, Yuyan | |
| 773 | 0 |
_tJournal of molecular modeling _gvol. 20 _gno. 11 _gp. 2515 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1007/s00894-014-2515-y _zAvailable from publisher's website |
| 999 |
_c24352045 _d24352045 |
||