| 000 | 01919 a2200529 4500 | ||
|---|---|---|---|
| 005 | 20250517002600.0 | ||
| 264 | 0 | _c20150908 | |
| 008 | 201509s 0 0 eng d | ||
| 022 | _a1520-6017 | ||
| 024 | 7 |
_a10.1002/jps.24214 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aThiel, Christoph | |
| 245 | 0 | 0 |
_aA systematic evaluation of the use of physiologically based pharmacokinetic modeling for cross-species extrapolation. _h[electronic resource] |
| 260 |
_bJournal of pharmaceutical sciences _cJan 2015 |
||
| 300 |
_a191-206 p. _bdigital |
||
| 500 | _aPublication Type: Comparative Study; Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAnimals |
| 650 | 0 | 4 | _aCells, Cultured |
| 650 | 0 | 4 | _aComputational Biology |
| 650 | 0 | 4 |
_aCytochrome P-450 Enzyme System _xgenetics |
| 650 | 0 | 4 |
_aDrug Evaluation, Preclinical _xmethods |
| 650 | 0 | 4 |
_aDrugs, Investigational _xmetabolism |
| 650 | 0 | 4 | _aGene Expression Profiling |
| 650 | 0 | 4 |
_aGene Expression Regulation _xdrug effects |
| 650 | 0 | 4 |
_aGene Expression Regulation, Enzymologic _xdrug effects |
| 650 | 0 | 4 | _aGermany |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 |
_aLiver _xcytology |
| 650 | 0 | 4 | _aMice, Inbred C57BL |
| 650 | 0 | 4 | _aModels, Biological |
| 650 | 0 | 4 | _aOrgan Specificity |
| 650 | 0 | 4 |
_aPharmacology, Clinical _xmethods |
| 650 | 0 | 4 |
_aPhysiology, Comparative _xmethods |
| 650 | 0 | 4 | _aSpecies Specificity |
| 650 | 0 | 4 | _aSpecific Pathogen-Free Organisms |
| 700 | 1 | _aSchneckener, Sebastian | |
| 700 | 1 | _aKrauss, Markus | |
| 700 | 1 | _aGhallab, Ahmed | |
| 700 | 1 | _aHofmann, Ute | |
| 700 | 1 | _aKanacher, Tobias | |
| 700 | 1 | _aZellmer, Sebastian | |
| 700 | 1 | _aGebhardt, Rolf | |
| 700 | 1 | _aHengstler, Jan G | |
| 700 | 1 | _aKuepfer, Lars | |
| 773 | 0 |
_tJournal of pharmaceutical sciences _gvol. 104 _gno. 1 _gp. 191-206 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1002/jps.24214 _zAvailable from publisher's website |
| 999 |
_c24351491 _d24351491 |
||