000			02125 a2200661 4500
005			20250517002520.0
264		0	_c20150421
008			201504s 0 0 eng d
022			_a1083-351X
024	7		_a10.1074/jbc.M114.608497 _2doi
040			_aNLM _beng _cNLM
100	1		_aDeng, Gejing
245	0	0	_aSelective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule. _h[electronic resource]
260			_bThe Journal of biological chemistry _cJan 2015
300			_a762-74 p. _bdigital
500			_aPublication Type: Journal Article
650	0	4	_aAllosteric Site
650	0	4	_aCrystallography, X-Ray
650	0	4	_aDNA Methylation _xgenetics
650	0	4	_aDrug Discovery
650	0	4	_aEnzyme Inhibitors _xchemical synthesis
650	0	4	_aEscherichia coli
650	0	4	_aGene Expression Regulation, Neoplastic
650	0	4	_aHumans
650	0	4	_aIsocitrate Dehydrogenase _xantagonists & inhibitors
650	0	4	_aMagnesium _xchemistry
650	0	4	_aMutant Proteins _xchemistry
650	0	4	_aNeoplasms _xdrug therapy
650	0	4	_aProtein Conformation
700	1		_aShen, Junqing
700	1		_aYin, Ming
700	1		_aMcManus, Jessica
700	1		_aMathieu, Magali
700	1		_aGee, Patricia
700	1		_aHe, Timothy
700	1		_aShi, Chaomei
700	1		_aBedel, Olivier
700	1		_aMcLean, Larry R
700	1		_aLe-Strat, Frank
700	1		_aZhang, Ying
700	1		_aMarquette, Jean-Pierre
700	1		_aGao, Qiang
700	1		_aZhang, Bailin
700	1		_aRak, Alexey
700	1		_aHoffmann, Dietmar
700	1		_aRooney, Eamonn
700	1		_aVassort, Aurelie
700	1		_aEnglaro, Walter
700	1		_aLi, Yi
700	1		_aPatel, Vinod
700	1		_aAdrian, Francisco
700	1		_aGross, Stefan
700	1		_aWiederschain, Dmitri
700	1		_aCheng, Hong
700	1		_aLicht, Stuart
773	0		_tThe Journal of biological chemistry _gvol. 290 _gno. 2 _gp. 762-74
856	4	0	_uhttps://doi.org/10.1074/jbc.M114.608497 _zAvailable from publisher's website
999			_c24349432 _d24349432