000 02320 a2200661 4500
005 20250517002041.0
264 0 _c20150604
008 201506s 0 0 eng d
022 _a1476-5551
024 7 _a10.1038/leu.2014.320
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHuelsemann, M F
245 0 0 _aHypoxia-induced p38 MAPK activation reduces Mcl-1 expression and facilitates sensitivity towards BH3 mimetics in chronic lymphocytic leukemia.
_h[electronic resource]
260 _bLeukemia
_cApr 2015
300 _a981-4 p.
_bdigital
500 _aPublication Type: Letter; Research Support, Non-U.S. Gov't
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aB-Lymphocytes
_xdrug effects
650 0 4 _aBendamustine Hydrochloride
650 0 4 _aBiphenyl Compounds
_xpharmacology
650 0 4 _aBridged Bicyclo Compounds, Heterocyclic
_xpharmacology
650 0 4 _aCD40 Ligand
_xgenetics
650 0 4 _aCell Hypoxia
650 0 4 _aCells, Cultured
650 0 4 _aDrug Resistance, Neoplasm
650 0 4 _aEnzyme Activation
650 0 4 _aGene Expression Regulation, Leukemic
650 0 4 _aHumans
650 0 4 _aLeukemia, Lymphocytic, Chronic, B-Cell
_xgenetics
650 0 4 _aMyeloid Cell Leukemia Sequence 1 Protein
_xantagonists & inhibitors
650 0 4 _aNitrogen Mustard Compounds
_xpharmacology
650 0 4 _aNitrophenols
_xpharmacology
650 0 4 _aOxygen
_xpharmacology
650 0 4 _aPiperazines
_xpharmacology
650 0 4 _aProto-Oncogene Proteins c-bcl-2
_xgenetics
650 0 4 _aSignal Transduction
650 0 4 _aSulfonamides
_xpharmacology
650 0 4 _aVidarabine
_xanalogs & derivatives
650 0 4 _abcl-X Protein
_xgenetics
650 0 4 _ap38 Mitogen-Activated Protein Kinases
_xgenetics
700 1 _aPatz, M
700 1 _aBeckmann, L
700 1 _aBrinkmann, K
700 1 _aOtto, T
700 1 _aFandrey, J
700 1 _aBecker, H J
700 1 _aTheurich, S
700 1 _avon Bergwelt-Baildon, M
700 1 _aPallasch, C P
700 1 _aZahedi, R P
700 1 _aKashkar, H
700 1 _aReinhardt, H C
700 1 _aHallek, M
700 1 _aWendtner, C M
700 1 _aFrenzel, L P
773 0 _tLeukemia
_gvol. 29
_gno. 4
_gp. 981-4
856 4 0 _uhttps://doi.org/10.1038/leu.2014.320
_zAvailable from publisher's website
999 _c24334914
_d24334914