| 000 | 02368 a2200637 4500 | ||
|---|---|---|---|
| 005 | 20250517001617.0 | ||
| 264 | 0 | _c20150918 | |
| 008 | 201509s 0 0 eng d | ||
| 022 | _a1573-0646 | ||
| 024 | 7 |
_a10.1007/s10637-014-0176-4 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aFalchook, Gerald S | |
| 245 | 0 | 0 |
_aDual antiangiogenic inhibition: a phase I dose escalation and expansion trial targeting VEGF-A and VEGFR in patients with advanced solid tumors. _h[electronic resource] |
| 260 |
_bInvestigational new drugs _cFeb 2015 |
||
| 300 |
_a215-24 p. _bdigital |
||
| 500 | _aPublication Type: Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural | ||
| 650 | 0 | 4 | _aAdult |
| 650 | 0 | 4 | _aAged |
| 650 | 0 | 4 | _aAged, 80 and over |
| 650 | 0 | 4 |
_aAngiogenesis Inhibitors _xadministration & dosage |
| 650 | 0 | 4 |
_aAntibodies, Monoclonal, Humanized _xadministration & dosage |
| 650 | 0 | 4 |
_aAntineoplastic Combined Chemotherapy Protocols _xadverse effects |
| 650 | 0 | 4 | _aBevacizumab |
| 650 | 0 | 4 | _aClass I Phosphatidylinositol 3-Kinases |
| 650 | 0 | 4 | _aFemale |
| 650 | 0 | 4 | _aHumans |
| 650 | 0 | 4 | _aMale |
| 650 | 0 | 4 | _aMiddle Aged |
| 650 | 0 | 4 | _aMutation |
| 650 | 0 | 4 |
_aNeoplasms _xdrug therapy |
| 650 | 0 | 4 |
_aNiacinamide _xadministration & dosage |
| 650 | 0 | 4 |
_aPTEN Phosphohydrolase _xgenetics |
| 650 | 0 | 4 |
_aPhenylurea Compounds _xadministration & dosage |
| 650 | 0 | 4 |
_aPhosphatidylinositol 3-Kinases _xgenetics |
| 650 | 0 | 4 | _aPolymorphism, Single Nucleotide |
| 650 | 0 | 4 |
_aProto-Oncogene Proteins _xgenetics |
| 650 | 0 | 4 |
_aReceptors, Vascular Endothelial Growth Factor _xantagonists & inhibitors |
| 650 | 0 | 4 | _aSorafenib |
| 650 | 0 | 4 |
_aTumor Suppressor Protein p53 _xgenetics |
| 650 | 0 | 4 |
_aVascular Endothelial Growth Factor A _xantagonists & inhibitors |
| 700 | 1 | _aWheler, Jennifer J | |
| 700 | 1 | _aNaing, Aung | |
| 700 | 1 | _aPiha-Paul, Sarina A | |
| 700 | 1 | _aFu, Siqing | |
| 700 | 1 | _aTsimberidou, Apostolia M | |
| 700 | 1 | _aHong, David S | |
| 700 | 1 | _aJanku, Filip | |
| 700 | 1 | _aZinner, Ralph | |
| 700 | 1 | _aJiang, Yunfang | |
| 700 | 1 | _aHuang, Mei | |
| 700 | 1 | _aLin, Quan | |
| 700 | 1 | _aParkhurst, Kristin | |
| 700 | 1 | _aKurzrock, Razelle | |
| 773 | 0 |
_tInvestigational new drugs _gvol. 33 _gno. 1 _gp. 215-24 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1007/s10637-014-0176-4 _zAvailable from publisher's website |
| 999 |
_c24322328 _d24322328 |
||