000			02208 a2200601 4500
005			20250517001520.0
264		0	_c20150223
008			201502s 0 0 eng d
022			_a1524-4636
024	7		_a10.1161/ATVBAHA.114.303899 _2doi
040			_aNLM _beng _cNLM
100	1		_aZhang, Donghong
245	0	0	_aHomocysteine accelerates senescence of endothelial cells via DNA hypomethylation of human telomerase reverse transcriptase. _h[electronic resource]
260			_bArteriosclerosis, thrombosis, and vascular biology _cJan 2015
300			_a71-8 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_aAngiotensin II _xmetabolism
650	0	4	_aAnimals
650	0	4	_aBinding Sites
650	0	4	_aCCCTC-Binding Factor
650	0	4	_aCells, Cultured
650	0	4	_aCellular Senescence _xdrug effects
650	0	4	_aCyclin-Dependent Kinase Inhibitor p16 _xmetabolism
650	0	4	_aCyclin-Dependent Kinase Inhibitor p21 _xmetabolism
650	0	4	_aDNA Methylation _xdrug effects
650	0	4	_aDisease Models, Animal
650	0	4	_aFolic Acid _xpharmacology
650	0	4	_aGene Expression Regulation, Enzymologic
650	0	4	_aHomocysteine _xpharmacology
650	0	4	_aHuman Umbilical Vein Endothelial Cells _xdrug effects
650	0	4	_aHumans
650	0	4	_aHyperhomocysteinemia _xblood
650	0	4	_aMale
650	0	4	_aMice, Inbred C57BL
650	0	4	_aPromoter Regions, Genetic
650	0	4	_aRNA Interference
650	0	4	_aRepressor Proteins _xgenetics
650	0	4	_aS-Adenosylmethionine _xpharmacology
650	0	4	_aSp1 Transcription Factor _xgenetics
650	0	4	_aTelomerase _xgenetics
650	0	4	_aTelomere _xdrug effects
650	0	4	_aTelomere Shortening _xdrug effects
650	0	4	_aTime Factors
650	0	4	_aTransfection
650	0	4	_aTumor Suppressor Protein p53 _xmetabolism
700	1		_aSun, Xiaoli
700	1		_aLiu, Jianlan
700	1		_aXie, Xina
700	1		_aCui, Wei
700	1		_aZhu, Yi
773	0		_tArteriosclerosis, thrombosis, and vascular biology _gvol. 35 _gno. 1 _gp. 71-8
856	4	0	_uhttps://doi.org/10.1161/ATVBAHA.114.303899 _zAvailable from publisher's website
999			_c24319114 _d24319114