000 02386 a2200577 4500
005 20250517001046.0
264 0 _c20150311
008 201503s 0 0 eng d
022 _a1522-1504
024 7 _a10.1152/ajplung.00217.2014
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHawkins, Arie
245 0 0 _aA non-BRICHOS SFTPC mutant (SP-CI73T) linked to interstitial lung disease promotes a late block in macroautophagy disrupting cellular proteostasis and mitophagy.
_h[electronic resource]
260 _bAmerican journal of physiology. Lung cellular and molecular physiology
_cJan 2015
300 _aL33-47 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
650 0 4 _aATP-Binding Cassette Transporters
_xgenetics
650 0 4 _aAdaptor Proteins, Signal Transducing
_xbiosynthesis
650 0 4 _aAmino Acid Substitution
650 0 4 _aAutophagy
650 0 4 _aAutophagy-Related Protein 8 Family
650 0 4 _aFemale
650 0 4 _aGene Expression Regulation
_xgenetics
650 0 4 _aGenetic Diseases, Inborn
_xgenetics
650 0 4 _aHEK293 Cells
650 0 4 _aHumans
650 0 4 _aInfant
650 0 4 _aLung Diseases, Interstitial
_xgenetics
650 0 4 _aLysosomes
_xgenetics
650 0 4 _aMembrane Potential, Mitochondrial
_xgenetics
650 0 4 _aMicrofilament Proteins
_xbiosynthesis
650 0 4 _aMicrotubule-Associated Proteins
_xbiosynthesis
650 0 4 _aMitochondria
_xgenetics
650 0 4 _aMutation, Missense
650 0 4 _aProteostasis Deficiencies
_xgenetics
650 0 4 _aPulmonary Surfactant-Associated Protein C
_xgenetics
650 0 4 _aSequestosome-1 Protein
650 0 4 _aUbiquitin-Protein Ligases
_xbiosynthesis
650 0 4 _aVacuoles
_xgenetics
650 0 4 _arab GTP-Binding Proteins
_xbiosynthesis
650 0 4 _arab7 GTP-Binding Proteins
700 1 _aGuttentag, Susan H
700 1 _aDeterding, Robin
700 1 _aFunkhouser, William K
700 1 _aGoralski, Jennifer L
700 1 _aChatterjee, Shampa
700 1 _aMulugeta, Surafel
700 1 _aBeers, Michael F
773 0 _tAmerican journal of physiology. Lung cellular and molecular physiology
_gvol. 308
_gno. 1
_gp. L33-47
856 4 0 _uhttps://doi.org/10.1152/ajplung.00217.2014
_zAvailable from publisher's website
999 _c24304852
_d24304852