000 01935 a2200505 4500
005 20250516235819.0
264 0 _c20160105
008 201601s 0 0 eng d
022 _a1096-0929
024 7 _a10.1093/toxsci/kfu215
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aTalbert, Dominique R
245 0 0 _aA multi-parameter in vitro screen in human stem cell-derived cardiomyocytes identifies ponatinib-induced structural and functional cardiac toxicity.
_h[electronic resource]
260 _bToxicological sciences : an official journal of the Society of Toxicology
_cJan 2015
300 _a147-55 p.
_bdigital
500 _aPublication Type: Journal Article
650 0 4 _aActin Cytoskeleton
_xdrug effects
650 0 4 _aAntineoplastic Agents
_xtoxicity
650 0 4 _aCell Death
_xdrug effects
650 0 4 _aCell Differentiation
650 0 4 _aCell Line
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aHeart Diseases
_xchemically induced
650 0 4 _aHeart Rate
_xdrug effects
650 0 4 _aHumans
650 0 4 _aImidazoles
_xtoxicity
650 0 4 _aInduced Pluripotent Stem Cells
_xdrug effects
650 0 4 _aMitochondria, Heart
_xdrug effects
650 0 4 _aMyocytes, Cardiac
_xdrug effects
650 0 4 _aOxidative Stress
_xdrug effects
650 0 4 _aProtein Kinase Inhibitors
_xtoxicity
650 0 4 _aPyridazines
_xtoxicity
650 0 4 _aRisk Assessment
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aTime Factors
650 0 4 _aToxicity Tests
_xmethods
650 0 4 _aTroponin
_xmetabolism
700 1 _aDoherty, Kimberly R
700 1 _aTrusk, Patricia B
700 1 _aMoran, Diarmuid M
700 1 _aShell, Scott A
700 1 _aBacus, Sarah
773 0 _tToxicological sciences : an official journal of the Society of Toxicology
_gvol. 143
_gno. 1
_gp. 147-55
856 4 0 _uhttps://doi.org/10.1093/toxsci/kfu215
_zAvailable from publisher's website
999 _c24267953
_d24267953