000 01690 a2200481 4500
005 20250516235337.0
264 0 _c20160414
008 201604s 0 0 eng d
022 _a1399-0047
024 7 _a10.1107/S1399004714017775
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aZáková, Lenka
245 0 0 _aHuman insulin analogues modified at the B26 site reveal a hormone conformation that is undetected in the receptor complex.
_h[electronic resource]
260 _bActa crystallographica. Section D, Biological crystallography
_cOct 2014
300 _a2765-74 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAmino Acid Substitution
650 0 4 _aAnimals
650 0 4 _aCells, Cultured
650 0 4 _aCrystallography, X-Ray
650 0 4 _aFibroblasts
_xmetabolism
650 0 4 _aHumans
650 0 4 _aInsulin
_xanalogs & derivatives
650 0 4 _aLymphocytes
_xmetabolism
650 0 4 _aMale
650 0 4 _aMice
650 0 4 _aMice, Knockout
650 0 4 _aModels, Molecular
650 0 4 _aMutation
650 0 4 _aPhenylalanine
650 0 4 _aProtein Conformation
650 0 4 _aRats, Wistar
650 0 4 _aReceptor, Insulin
_xchemistry
700 1 _aKletvíková, Emília
700 1 _aLepšík, Martin
700 1 _aCollinsová, Michaela
700 1 _aWatson, Christopher J
700 1 _aTurkenburg, Johan P
700 1 _aJiráček, Jiří
700 1 _aBrzozowski, Andrzej M
773 0 _tActa crystallographica. Section D, Biological crystallography
_gvol. 70
_gno. Pt 10
_gp. 2765-74
856 4 0 _uhttps://doi.org/10.1107/S1399004714017775
_zAvailable from publisher's website
999 _c24252388
_d24252388