000			02299 a2200685 4500
005			20250516231828.0
264		0	_c20141111
008			201411s 0 0 eng d
022			_a1878-3686
024	7		_a10.1016/j.ccr.2014.07.015 _2doi
040			_aNLM _beng _cNLM
100	1		_aGustafson, William Clay
245	0	0	_aDrugging MYCN through an allosteric transition in Aurora kinase A. _h[electronic resource]
260			_bCancer cell _cSep 2014
300			_a414-427 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650	0	4	_aAllosteric Regulation
650	0	4	_aAnimals
650	0	4	_aAntineoplastic Agents _xchemistry
650	0	4	_aArea Under Curve
650	0	4	_aAurora Kinase A _xantagonists & inhibitors
650	0	4	_aCatalytic Domain
650	0	4	_aCell Line, Tumor
650	0	4	_aCell Survival _xdrug effects
650	0	4	_aCrystallography, X-Ray
650	0	4	_aHumans
650	0	4	_aMice
650	0	4	_aMice, Inbred NOD
650	0	4	_aMice, Nude
650	0	4	_aMice, SCID
650	0	4	_aModels, Molecular
650	0	4	_aN-Myc Proto-Oncogene Protein
650	0	4	_aNeuroblastoma _xdrug therapy
650	0	4	_aNuclear Proteins _xchemistry
650	0	4	_aOncogene Proteins _xchemistry
650	0	4	_aPhenylurea Compounds _xchemistry
650	0	4	_aPhosphorylation
650	0	4	_aProtein Processing, Post-Translational
650	0	4	_aProtein Structure, Secondary
650	0	4	_aProteolysis
650	0	4	_aPyrimidines _xchemistry
650	0	4	_aS Phase Cell Cycle Checkpoints _xdrug effects
650	0	4	_aStructure-Activity Relationship
650	0	4	_aTumor Burden _xdrug effects
650	0	4	_aXenograft Model Antitumor Assays
700	1		_aMeyerowitz, Justin Gabriel
700	1		_aNekritz, Erin A
700	1		_aChen, Justin
700	1		_aBenes, Cyril
700	1		_aCharron, Elise
700	1		_aSimonds, Erin F
700	1		_aSeeger, Robert
700	1		_aMatthay, Katherine K
700	1		_aHertz, Nicholas T
700	1		_aEilers, Martin
700	1		_aShokat, Kevan M
700	1		_aWeiss, William A
773	0		_tCancer cell _gvol. 26 _gno. 3 _gp. 414-427
856	4	0	_uhttps://doi.org/10.1016/j.ccr.2014.07.015 _zAvailable from publisher's website
999			_c24147776 _d24147776