000			02321 a2200685 4500
005			20250516230822.0
264		0	_c20141222
008			201412s 0 0 eng d
022			_a1538-7445
024	7		_a10.1158/0008-5472.CAN-14-0799 _2doi
040			_aNLM _beng _cNLM
100	1		_aWang, Shaomeng
245	0	0	_aSAR405838: an optimized inhibitor of MDM2-p53 interaction that induces complete and durable tumor regression. _h[electronic resource]
260			_bCancer research _cOct 2014
300			_a5855-65 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
650	0	4	_aAnimals
650	0	4	_aAntineoplastic Agents _xpharmacology
650	0	4	_aApoptosis _xdrug effects
650	0	4	_aApoptosis Regulatory Proteins _xmetabolism
650	0	4	_aCell Cycle Checkpoints
650	0	4	_aCell Proliferation _xdrug effects
650	0	4	_aDogs
650	0	4	_aDrug Stability
650	0	4	_aHCT116 Cells
650	0	4	_aHumans
650	0	4	_aIndoles _xpharmacology
650	0	4	_aMice
650	0	4	_aProtein Binding
650	0	4	_aProto-Oncogene Proteins _xmetabolism
650	0	4	_aProto-Oncogene Proteins c-mdm2 _xmetabolism
650	0	4	_aRats
650	0	4	_aRemission Induction
650	0	4	_aSpiro Compounds _xpharmacology
650	0	4	_aTumor Suppressor Protein p53 _xmetabolism
650	0	4	_aXenograft Model Antitumor Assays
700	1		_aSun, Wei
700	1		_aZhao, Yujun
700	1		_aMcEachern, Donna
700	1		_aMeaux, Isabelle
700	1		_aBarrière, Cédric
700	1		_aStuckey, Jeanne A
700	1		_aMeagher, Jennifer L
700	1		_aBai, Longchuan
700	1		_aLiu, Liu
700	1		_aHoffman-Luca, Cassandra Gianna
700	1		_aLu, Jianfeng
700	1		_aShangary, Sanjeev
700	1		_aYu, Shanghai
700	1		_aBernard, Denzil
700	1		_aAguilar, Angelo
700	1		_aDos-Santos, Odette
700	1		_aBesret, Laurent
700	1		_aGuerif, Stéphane
700	1		_aPannier, Pascal
700	1		_aGorge-Bernat, Dimitri
700	1		_aDebussche, Laurent
773	0		_tCancer research _gvol. 74 _gno. 20 _gp. 5855-65
856	4	0	_uhttps://doi.org/10.1158/0008-5472.CAN-14-0799 _zAvailable from publisher's website
999			_c24119312 _d24119312