000 01842 a2200517 4500
005 20250516230112.0
264 0 _c20151102
008 201511s 0 0 eng d
022 _a1948-7193
024 7 _a10.1021/cn500119g
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aWang, Zhiren
245 0 0 _aDesign, synthesis, and evaluation of multitarget-directed selenium-containing clioquinol derivatives for the treatment of Alzheimer's disease.
_h[electronic resource]
260 _bACS chemical neuroscience
_cOct 2014
300 _a952-62 p.
_bdigital
500 _aPublication Type: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAlzheimer Disease
_xdrug therapy
650 0 4 _aAmyloid beta-Peptides
_xmetabolism
650 0 4 _aAnimals
650 0 4 _aAntioxidants
_xchemical synthesis
650 0 4 _aBlood-Brain Barrier
_xmetabolism
650 0 4 _aCapillary Permeability
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aClioquinol
_xanalogs & derivatives
650 0 4 _aCopper
_xtoxicity
650 0 4 _aDrug Design
650 0 4 _aDrug Evaluation, Preclinical
650 0 4 _aHumans
650 0 4 _aHydrogen Peroxide
_xmetabolism
650 0 4 _aMembranes, Artificial
650 0 4 _aModels, Biological
650 0 4 _aNootropic Agents
_xchemical synthesis
650 0 4 _aPeptide Fragments
_xmetabolism
650 0 4 _aProtein Multimerization
_xdrug effects
650 0 4 _aSelenium Compounds
_xchemical synthesis
650 0 4 _aSwine
700 1 _aWang, Yali
700 1 _aLi, Wenrui
700 1 _aMao, Fei
700 1 _aSun, Yang
700 1 _aHuang, Ling
700 1 _aLi, Xingshu
773 0 _tACS chemical neuroscience
_gvol. 5
_gno. 10
_gp. 952-62
856 4 0 _uhttps://doi.org/10.1021/cn500119g
_zAvailable from publisher's website
999 _c24096327
_d24096327