000 02271 a2200649 4500
005 20250516223719.0
264 0 _c20150130
008 201501s 0 0 eng d
022 _a1528-0012
024 7 _a10.1053/j.gastro.2014.07.019
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aBerger, Carola
245 0 0 _aDaclatasvir-like inhibitors of NS5A block early biogenesis of hepatitis C virus-induced membranous replication factories, independent of RNA replication.
_h[electronic resource]
260 _bGastroenterology
_cNov 2014
300 _a1094-105.e25 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAntiviral Agents
_xchemistry
650 0 4 _aBinding Sites
650 0 4 _aCarbamates
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Membrane
_xdrug effects
650 0 4 _aDrug Design
650 0 4 _aDrug Resistance, Viral
650 0 4 _aHepacivirus
_xdrug effects
650 0 4 _aHepatocytes
_xdrug effects
650 0 4 _aHost-Pathogen Interactions
650 0 4 _aHumans
650 0 4 _aImidazoles
_xchemistry
650 0 4 _aMinor Histocompatibility Antigens
650 0 4 _aMolecular Docking Simulation
650 0 4 _aMolecular Structure
650 0 4 _aMutation
650 0 4 _aPhosphotransferases (Alcohol Group Acceptor)
_xmetabolism
650 0 4 _aProtease Inhibitors
_xchemistry
650 0 4 _aProtein Conformation
650 0 4 _aProtein Multimerization
650 0 4 _aPyrrolidines
650 0 4 _aStructure-Activity Relationship
650 0 4 _aTime Factors
650 0 4 _aTransfection
650 0 4 _aValine
_xanalogs & derivatives
650 0 4 _aViral Nonstructural Proteins
_xantagonists & inhibitors
650 0 4 _aVirus Replication
_xdrug effects
700 1 _aRomero-Brey, Inés
700 1 _aRadujkovic, Danijela
700 1 _aTerreux, Raphael
700 1 _aZayas, Margarita
700 1 _aPaul, David
700 1 _aHarak, Christian
700 1 _aHoppe, Simone
700 1 _aGao, Min
700 1 _aPenin, Francois
700 1 _aLohmann, Volker
700 1 _aBartenschlager, Ralf
773 0 _tGastroenterology
_gvol. 147
_gno. 5
_gp. 1094-105.e25
856 4 0 _uhttps://doi.org/10.1053/j.gastro.2014.07.019
_zAvailable from publisher's website
999 _c24027608
_d24027608