000 01480 a2200397 4500
005 20250516220053.0
264 0 _c20150330
008 201503s 0 0 eng d
022 _a1768-3254
024 7 _a10.1016/j.ejmech.2014.05.074
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aAbdelsamie, Ahmed S
245 0 0 _aInhibition of 17β-HSD1: SAR of bicyclic substituted hydroxyphenylmethanones and discovery of new potent inhibitors with thioether linker.
_h[electronic resource]
260 _bEuropean journal of medicinal chemistry
_cJul 2014
300 _a394-406 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _a17-Hydroxysteroid Dehydrogenases
_xantagonists & inhibitors
650 0 4 _aAnimals
650 0 4 _aDose-Response Relationship, Drug
650 0 4 _aDrug Discovery
650 0 4 _aEnzyme Inhibitors
_xchemical synthesis
650 0 4 _aHumans
650 0 4 _aMice
650 0 4 _aModels, Molecular
650 0 4 _aMolecular Structure
650 0 4 _aPhenols
_xchemical synthesis
650 0 4 _aStructure-Activity Relationship
650 0 4 _aSulfides
_xchemistry
700 1 _aBey, Emmanuel
700 1 _aHanke, Nina
700 1 _aEmpting, Martin
700 1 _aHartmann, Rolf W
700 1 _aFrotscher, Martin
773 0 _tEuropean journal of medicinal chemistry
_gvol. 82
_gp. 394-406
856 4 0 _uhttps://doi.org/10.1016/j.ejmech.2014.05.074
_zAvailable from publisher's website
999 _c23918689
_d23918689