000 01926 a2200517 4500
005 20250516215553.0
264 0 _c20150427
008 201504s 0 0 eng d
022 _a1528-0020
024 7 _a10.1182/blood-2013-10-534842
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aZhu, Jianqiong
245 0 0 _aHydroxyurea-inducible SAR1 gene acts through the Giα/JNK/Jun pathway to regulate γ-globin expression.
_h[electronic resource]
260 _bBlood
_cAug 2014
300 _a1146-56 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Intramural
650 0 4 _aAntineoplastic Agents
_xpharmacology
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aBinding Sites
_xgenetics
650 0 4 _aBlotting, Western
650 0 4 _aCell Cycle Checkpoints
_xdrug effects
650 0 4 _aCells, Cultured
650 0 4 _aFetal Hemoglobin
_xgenetics
650 0 4 _aGTP-Binding Protein alpha Subunits, Gi-Go
_xmetabolism
650 0 4 _aGene Expression
_xdrug effects
650 0 4 _aHumans
650 0 4 _aHydroxyurea
_xpharmacology
650 0 4 _aJNK Mitogen-Activated Protein Kinases
_xmetabolism
650 0 4 _aK562 Cells
650 0 4 _aMonomeric GTP-Binding Proteins
_xgenetics
650 0 4 _aNF-kappa B
_xmetabolism
650 0 4 _aPromoter Regions, Genetic
_xgenetics
650 0 4 _aProto-Oncogene Proteins c-jun
_xmetabolism
650 0 4 _aRNA Interference
650 0 4 _aReverse Transcriptase Polymerase Chain Reaction
650 0 4 _aSignal Transduction
_xdrug effects
650 0 4 _aets-Domain Protein Elk-1
_xmetabolism
650 0 4 _agamma-Globins
_xgenetics
700 1 _aChin, Kyung
700 1 _aAerbajinai, Wulin
700 1 _aKumkhaek, Chutima
700 1 _aLi, Hongzhen
700 1 _aRodgers, Griffin P
773 0 _tBlood
_gvol. 124
_gno. 7
_gp. 1146-56
856 4 0 _uhttps://doi.org/10.1182/blood-2013-10-534842
_zAvailable from publisher's website
999 _c23904432
_d23904432