000 01810 a2200481 4500
005 20250516215511.0
264 0 _c20150730
008 201507s 0 0 eng d
022 _a1932-6203
024 7 _a10.1371/journal.pone.0099211
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aHanafi, Laïla-Aïcha
245 0 0 _aFludarabine downregulates indoleamine 2,3-dioxygenase in tumors via a proteasome-mediated degradation mechanism.
_h[electronic resource]
260 _bPloS one
_c2014
300 _ae99211 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAntineoplastic Agents
_xtoxicity
650 0 4 _aB7-H1 Antigen
_xmetabolism
650 0 4 _aDown-Regulation
_xdrug effects
650 0 4 _aHistocompatibility Antigens Class I
_xmetabolism
650 0 4 _aHumans
650 0 4 _aIndoleamine-Pyrrole 2,3,-Dioxygenase
_xgenetics
650 0 4 _aInterferon-gamma
_xpharmacology
650 0 4 _aPhosphorylation
_xdrug effects
650 0 4 _aProteasome Endopeptidase Complex
_xmetabolism
650 0 4 _aProtein Stability
650 0 4 _aRNA Interference
650 0 4 _aRNA, Messenger
_xmetabolism
650 0 4 _aRNA, Small Interfering
_xmetabolism
650 0 4 _aSTAT1 Transcription Factor
_xantagonists & inhibitors
650 0 4 _aT-Lymphocytes
_ximmunology
650 0 4 _aTumor Cells, Cultured
650 0 4 _aVidarabine
_xanalogs & derivatives
700 1 _aGauchat, Dominique
700 1 _aGodin-Ethier, Jessica
700 1 _aPossamaï, David
700 1 _aDuvignaud, Jean-Baptiste
700 1 _aLeclerc, Denis
700 1 _aGrandvaux, Nathalie
700 1 _aLapointe, Réjean
773 0 _tPloS one
_gvol. 9
_gno. 6
_gp. e99211
856 4 0 _uhttps://doi.org/10.1371/journal.pone.0099211
_zAvailable from publisher's website
999 _c23902234
_d23902234