000 02289 a2200673 4500
005 20250516212409.0
264 0 _c20150420
008 201504s 0 0 eng d
022 _a2211-1247
024 7 _a10.1016/j.celrep.2014.04.014
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aPirazzoli, Valentina
245 0 0 _aAcquired resistance of EGFR-mutant lung adenocarcinomas to afatinib plus cetuximab is associated with activation of mTORC1.
_h[electronic resource]
260 _bCell reports
_cMay 2014
300 _a999-1008 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAdenocarcinoma
_xdrug therapy
650 0 4 _aAdenocarcinoma of Lung
650 0 4 _aAfatinib
650 0 4 _aAnimals
650 0 4 _aAntibodies, Monoclonal, Humanized
_xadministration & dosage
650 0 4 _aAntineoplastic Combined Chemotherapy Protocols
_xpharmacology
650 0 4 _aCell Line, Tumor
650 0 4 _aCetuximab
650 0 4 _aDrug Resistance, Neoplasm
650 0 4 _aErbB Receptors
_xgenetics
650 0 4 _aHumans
650 0 4 _aLung Neoplasms
_xdrug therapy
650 0 4 _aMechanistic Target of Rapamycin Complex 1
650 0 4 _aMice
650 0 4 _aMice, Nude
650 0 4 _aMice, Transgenic
650 0 4 _aMultiprotein Complexes
_xmetabolism
650 0 4 _aMutation
650 0 4 _aQuinazolines
_xadministration & dosage
650 0 4 _aRandom Allocation
650 0 4 _aTOR Serine-Threonine Kinases
_xmetabolism
650 0 4 _aXenograft Model Antitumor Assays
700 1 _aNebhan, Caroline
700 1 _aSong, Xiaoling
700 1 _aWurtz, Anna
700 1 _aWalther, Zenta
700 1 _aCai, Guoping
700 1 _aZhao, Zhongming
700 1 _aJia, Peilin
700 1 _ade Stanchina, Elisa
700 1 _aShapiro, Erik M
700 1 _aGale, Molly
700 1 _aYin, Ruonan
700 1 _aHorn, Leora
700 1 _aCarbone, David P
700 1 _aStephens, Philip J
700 1 _aMiller, Vincent
700 1 _aGettinger, Scott
700 1 _aPao, William
700 1 _aPoliti, Katerina
773 0 _tCell reports
_gvol. 7
_gno. 4
_gp. 999-1008
856 4 0 _uhttps://doi.org/10.1016/j.celrep.2014.04.014
_zAvailable from publisher's website
999 _c23812029
_d23812029