000 02371 a2200721 4500
005 20250516212134.0
264 0 _c20150804
008 201508s 0 0 eng d
022 _a2041-1723
024 7 _a10.1038/ncomms4814
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLee, Jung-Hoon
245 0 0 _aProtein grafting of p53TAD onto a leucine zipper scaffold generates a potent HDM dual inhibitor.
_h[electronic resource]
260 _bNature communications
_cMay 2014
300 _a3814 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650 0 4 _aAmino Acid Sequence
650 0 4 _aAnimals
650 0 4 _aApoptosis
_xgenetics
650 0 4 _aCell Cycle Checkpoints
_xgenetics
650 0 4 _aCell Cycle Proteins
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aCell Survival
_xdrug effects
650 0 4 _aCrystallography, X-Ray
650 0 4 _aFemale
650 0 4 _aHCT116 Cells
650 0 4 _aHumans
650 0 4 _aLeucine Zippers
_xgenetics
650 0 4 _aMice
650 0 4 _aMice, Inbred BALB C
650 0 4 _aMice, Nude
650 0 4 _aMolecular Dynamics Simulation
650 0 4 _aMultiprotein Complexes
_xultrastructure
650 0 4 _aNeoplasm Transplantation
650 0 4 _aNeoplasms
_xdrug therapy
650 0 4 _aNuclear Proteins
_xantagonists & inhibitors
650 0 4 _aProtein Engineering
650 0 4 _aProtein Structure, Tertiary
650 0 4 _aProto-Oncogene Proteins
_xantagonists & inhibitors
650 0 4 _aProto-Oncogene Proteins c-mdm2
_xantagonists & inhibitors
650 0 4 _aRecombinant Proteins
_xpharmacology
650 0 4 _aSequence Alignment
650 0 4 _aTransplantation, Heterologous
650 0 4 _aTumor Suppressor Protein p53
_xchemistry
700 1 _aKang, Eunji
700 1 _aLee, Jungmin
700 1 _aKim, Jungmin
700 1 _aLee, Kyoung Hu
700 1 _aHan, Jieun
700 1 _aKang, Hye Yoon
700 1 _aAhn, Soshin
700 1 _aOh, Youngmi
700 1 _aShin, Dongkyu
700 1 _aHur, Kyeyeon
700 1 _aChae, Su Young
700 1 _aSong, Paul H
700 1 _aKim, Yong-In
700 1 _aPark, Jae Chan
700 1 _aLee, Jae Il
773 0 _tNature communications
_gvol. 5
_gp. 3814
856 4 0 _uhttps://doi.org/10.1038/ncomms4814
_zAvailable from publisher's website
999 _c23803851
_d23803851