000 02072 a2200577 4500
005 20250516210647.0
264 0 _c20141029
008 201410s 0 0 eng d
022 _a1474-9726
024 7 _a10.1111/acel.12181
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLi, Baomin
245 0 0 _aDownregulation of the Werner syndrome protein induces a metabolic shift that compromises redox homeostasis and limits proliferation of cancer cells.
_h[electronic resource]
260 _bAging cell
_c04 2014
300 _a367-78 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural
650 0 4 _aAnimals
650 0 4 _aAntioxidants
_xpharmacology
650 0 4 _aCell Line, Tumor
650 0 4 _aCell Proliferation
_xdrug effects
650 0 4 _aCell Respiration
_xdrug effects
650 0 4 _aCellular Senescence
_xdrug effects
650 0 4 _aDNA Damage
650 0 4 _aDown-Regulation
_xdrug effects
650 0 4 _aEnergy Metabolism
_xdrug effects
650 0 4 _aExodeoxyribonucleases
_xgenetics
650 0 4 _aGene Knockdown Techniques
650 0 4 _aGlutathione
_xmetabolism
650 0 4 _aHomeostasis
_xdrug effects
650 0 4 _aHumans
650 0 4 _aHypoxia-Inducible Factor 1, alpha Subunit
_xmetabolism
650 0 4 _aMacromolecular Substances
_xmetabolism
650 0 4 _aMice
650 0 4 _aMitochondria
_xdrug effects
650 0 4 _aNeoplasms
_xmetabolism
650 0 4 _aNiacinamide
_xmetabolism
650 0 4 _aOxidation-Reduction
_xdrug effects
650 0 4 _aOxidative Stress
_xdrug effects
650 0 4 _aReactive Oxygen Species
_xmetabolism
650 0 4 _aRecQ Helicases
_xgenetics
650 0 4 _aWerner Syndrome
_xgenetics
650 0 4 _aWerner Syndrome Helicase
700 1 _aIglesias-Pedraz, Juan Manuel
700 1 _aChen, Leng-Ying
700 1 _aYin, Fei
700 1 _aCadenas, Enrique
700 1 _aReddy, Sita
700 1 _aComai, Lucio
773 0 _tAging cell
_gvol. 13
_gno. 2
_gp. 367-78
856 4 0 _uhttps://doi.org/10.1111/acel.12181
_zAvailable from publisher's website
999 _c23761303
_d23761303