000 02458 a2200709 4500
005 20250516210256.0
264 0 _c20150615
008 201506s 0 0 eng d
022 _a1932-7420
024 7 _a10.1016/j.cmet.2014.03.018
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aLiu, Meilian
245 0 0 _aGrb10 promotes lipolysis and thermogenesis by phosphorylation-dependent feedback inhibition of mTORC1.
_h[electronic resource]
260 _bCell metabolism
_cJun 2014
300 _a967-80 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAdaptor Proteins, Signal Transducing
_xmetabolism
650 0 4 _aAdipose Tissue, Brown
_xmetabolism
650 0 4 _aAdipose Tissue, White
_xmetabolism
650 0 4 _aAnimals
650 0 4 _aAntibiotics, Antineoplastic
_xpharmacology
650 0 4 _aCells, Cultured
650 0 4 _aCold Temperature
650 0 4 _aCold-Shock Response
650 0 4 _aDiabetes Mellitus
650 0 4 _aEnergy Metabolism
_xphysiology
650 0 4 _aFeedback, Physiological
650 0 4 _aGRB10 Adaptor Protein
_xbiosynthesis
650 0 4 _aInsulin Resistance
650 0 4 _aLipolysis
_xphysiology
650 0 4 _aMechanistic Target of Rapamycin Complex 1
650 0 4 _aMice
650 0 4 _aMice, Knockout
650 0 4 _aMultiprotein Complexes
_xantagonists & inhibitors
650 0 4 _aObesity
650 0 4 _aPhosphatidylinositol 3-Kinases
650 0 4 _aPhosphorylation
650 0 4 _aProtein Binding
650 0 4 _aProto-Oncogene Proteins c-akt
650 0 4 _aReceptor, Insulin
_xmetabolism
650 0 4 _aRegulatory-Associated Protein of mTOR
650 0 4 _aSignal Transduction
_xphysiology
650 0 4 _aSirolimus
_xpharmacology
650 0 4 _aTOR Serine-Threonine Kinases
_xantagonists & inhibitors
650 0 4 _aThermogenesis
_xphysiology
700 1 _aBai, Juli
700 1 _aHe, Sijia
700 1 _aVillarreal, Ricardo
700 1 _aHu, Derong
700 1 _aZhang, Chuntao
700 1 _aYang, Xin
700 1 _aLiang, Huiyun
700 1 _aSlaga, Thomas J
700 1 _aYu, Yonghao
700 1 _aZhou, Zhiguang
700 1 _aBlenis, John
700 1 _aScherer, Philipp E
700 1 _aDong, Lily Q
700 1 _aLiu, Feng
773 0 _tCell metabolism
_gvol. 19
_gno. 6
_gp. 967-80
856 4 0 _uhttps://doi.org/10.1016/j.cmet.2014.03.018
_zAvailable from publisher's website
999 _c23750827
_d23750827