000 01867 a2200505 4500
005 20250516210132.0
264 0 _c20140808
008 201408s 0 0 eng d
022 _a1520-4804
024 7 _a10.1021/jm500033r
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aVidenović, Milica
245 0 0 _aSecond generation steroidal 4-aminoquinolines are potent, dual-target inhibitors of the botulinum neurotoxin serotype A metalloprotease and P. falciparum malaria.
_h[electronic resource]
260 _bJournal of medicinal chemistry
_cMay 2014
300 _a4134-53 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAminoquinolines
_xchemical synthesis
650 0 4 _aAnimals
650 0 4 _aAntimalarials
_xchemical synthesis
650 0 4 _aBotulinum Toxins, Type A
_xantagonists & inhibitors
650 0 4 _aChick Embryo
650 0 4 _aChloroquine
_xpharmacology
650 0 4 _aDrug Resistance
650 0 4 _aHep G2 Cells
650 0 4 _aHumans
650 0 4 _aMetalloproteases
_xdrug effects
650 0 4 _aMolecular Docking Simulation
650 0 4 _aPlasmodium falciparum
_xdrug effects
650 0 4 _aProtease Inhibitors
_xchemical synthesis
650 0 4 _aStructure-Activity Relationship
700 1 _aOpsenica, Dejan M
700 1 _aBurnett, James C
700 1 _aGomba, Laura
700 1 _aNuss, Jonathan E
700 1 _aSelaković, Zivota
700 1 _aKonstantinović, Jelena
700 1 _aKrstić, Maja
700 1 _aSegan, Sandra
700 1 _aZlatović, Mario
700 1 _aSciotti, Richard J
700 1 _aBavari, Sina
700 1 _aSolaja, Bogdan A
773 0 _tJournal of medicinal chemistry
_gvol. 57
_gno. 10
_gp. 4134-53
856 4 0 _uhttps://doi.org/10.1021/jm500033r
_zAvailable from publisher's website
999 _c23746412
_d23746412