| 000 | 01728 a2200505 4500 | ||
|---|---|---|---|
| 005 | 20250516205710.0 | ||
| 264 | 0 | _c20140715 | |
| 008 | 201407s 0 0 eng d | ||
| 022 | _a1552-4469 | ||
| 024 | 7 |
_a10.1038/nchembio.1502 _2doi |
|
| 040 |
_aNLM _beng _cNLM |
||
| 100 | 1 | _aSykora, Jan | |
| 245 | 0 | 0 |
_aDynamics and hydration explain failed functional transformation in dehalogenase design. _h[electronic resource] |
| 260 |
_bNature chemical biology _cJun 2014 |
||
| 300 |
_a428-30 p. _bdigital |
||
| 500 | _aPublication Type: Journal Article; Research Support, Non-U.S. Gov't | ||
| 650 | 0 | 4 | _aAmino Acid Sequence |
| 650 | 0 | 4 | _aCatalysis |
| 650 | 0 | 4 | _aCatalytic Domain |
| 650 | 0 | 4 | _aCrystallography, X-Ray |
| 650 | 0 | 4 |
_aHydrocarbons, Brominated _xchemistry |
| 650 | 0 | 4 |
_aHydrolases _xchemistry |
| 650 | 0 | 4 | _aMolecular Dynamics Simulation |
| 650 | 0 | 4 | _aMolecular Sequence Data |
| 650 | 0 | 4 | _aMutagenesis, Site-Directed |
| 650 | 0 | 4 | _aProtein Conformation |
| 650 | 0 | 4 | _aProtein Engineering |
| 650 | 0 | 4 | _aSpectrometry, Fluorescence |
| 650 | 0 | 4 | _aSpectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization |
| 650 | 0 | 4 | _aStereoisomerism |
| 650 | 0 | 4 |
_aWater _xchemistry |
| 700 | 1 | _aBrezovsky, Jan | |
| 700 | 1 | _aKoudelakova, Tana | |
| 700 | 1 | _aLahoda, Maryna | |
| 700 | 1 | _aFortova, Andrea | |
| 700 | 1 | _aChernovets, Tatsiana | |
| 700 | 1 | _aChaloupkova, Radka | |
| 700 | 1 | _aStepankova, Veronika | |
| 700 | 1 | _aProkop, Zbynek | |
| 700 | 1 | _aSmatanova, Ivana Kuta | |
| 700 | 1 | _aHof, Martin | |
| 700 | 1 | _aDamborsky, Jiri | |
| 773 | 0 |
_tNature chemical biology _gvol. 10 _gno. 6 _gp. 428-30 |
|
| 856 | 4 | 0 |
_uhttps://doi.org/10.1038/nchembio.1502 _zAvailable from publisher's website |
| 999 |
_c23732934 _d23732934 |
||