000 02287 a2200613 4500
005 20250516203957.0
264 0 _c20150106
008 201501s 0 0 eng d
022 _a1873-4596
024 7 _a10.1016/j.freeradbiomed.2014.03.018
_2doi
040 _aNLM
_beng
_cNLM
100 1 _aZhang, Yingmei
245 0 0 _aMitochondrial aldehyde dehydrogenase 2 accentuates aging-induced cardiac remodeling and contractile dysfunction: role of AMPK, Sirt1, and mitochondrial function.
_h[electronic resource]
260 _bFree radical biology & medicine
_cJun 2014
300 _a208-220 p.
_bdigital
500 _aPublication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 0 4 _aAMP-Activated Protein Kinases
_xgenetics
650 0 4 _aAging
_xmetabolism
650 0 4 _aAldehyde Dehydrogenase
_xgenetics
650 0 4 _aAldehyde Dehydrogenase, Mitochondrial
650 0 4 _aAnimals
650 0 4 _aApoptosis
_xdrug effects
650 0 4 _aAtrial Remodeling
_xgenetics
650 0 4 _aBenzamides
_xpharmacology
650 0 4 _aBenzodioxoles
_xpharmacology
650 0 4 _aCalcium
_xmetabolism
650 0 4 _aCardiomegaly
_xenzymology
650 0 4 _aFibrosis
650 0 4 _aGene Expression Regulation
650 0 4 _aHeterocyclic Compounds, 4 or More Rings
_xpharmacology
650 0 4 _aIon Channels
_xgenetics
650 0 4 _aMice
650 0 4 _aMice, Transgenic
650 0 4 _aMitochondria, Heart
_xdrug effects
650 0 4 _aMitochondrial Proteins
_xgenetics
650 0 4 _aMyocardial Contraction
650 0 4 _aMyocardium
_xenzymology
650 0 4 _aPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
650 0 4 _aResveratrol
650 0 4 _aSignal Transduction
650 0 4 _aSirtuin 1
_xgenetics
650 0 4 _aStilbenes
_xpharmacology
650 0 4 _aSuperoxides
_xmetabolism
650 0 4 _aTranscription Factors
_xgenetics
650 0 4 _aUncoupling Protein 2
700 1 _aMi, Shou-Ling
700 1 _aHu, Nan
700 1 _aDoser, Thomas A
700 1 _aSun, Aijun
700 1 _aGe, Junbo
700 1 _aRen, Jun
773 0 _tFree radical biology & medicine
_gvol. 71
_gp. 208-220
856 4 0 _uhttps://doi.org/10.1016/j.freeradbiomed.2014.03.018
_zAvailable from publisher's website
999 _c23682792
_d23682792