000			02027 a2200553 4500
005			20250516203119.0
264		0	_c20140802
008			201408s 0 0 eng d
022			_a1083-351X
024	7		_a10.1074/jbc.C113.543736 _2doi
040			_aNLM _beng _cNLM
100	1		_aMazhab-Jafari, Mohammad T
245	0	0	_aStructure-guided mutation of the conserved G3-box glycine in Rheb generates a constitutively activated regulator of mammalian target of rapamycin (mTOR). _h[electronic resource]
260			_bThe Journal of biological chemistry _cMay 2014
300			_a12195-201 p. _bdigital
500			_aPublication Type: Journal Article; Research Support, Non-U.S. Gov't
650	0	4	_aAlanine _xchemistry
650	0	4	_aAmino Acid Motifs _xgenetics
650	0	4	_aAnimals
650	0	4	_aBinding Sites _xgenetics
650	0	4	_aCells, Cultured
650	0	4	_aCrystallography, X-Ray
650	0	4	_aGlycine _xchemistry
650	0	4	_aGuanosine Triphosphate _xchemistry
650	0	4	_aHeLa Cells
650	0	4	_aHumans
650	0	4	_aHydrolysis
650	0	4	_aMechanistic Target of Rapamycin Complex 1
650	0	4	_aMice
650	0	4	_aModels, Molecular
650	0	4	_aMonomeric GTP-Binding Proteins _xchemistry
650	0	4	_aMultiprotein Complexes _xgenetics
650	0	4	_aMutation
650	0	4	_aNeuropeptides _xchemistry
650	0	4	_aPhosphorylation
650	0	4	_aProtein Binding _xgenetics
650	0	4	_aProtein Structure, Tertiary
650	0	4	_aRas Homolog Enriched in Brain Protein
650	0	4	_aRibosomal Protein S6 Kinases, 70-kDa _xmetabolism
650	0	4	_aSignal Transduction _xgenetics
650	0	4	_aTOR Serine-Threonine Kinases _xgenetics
700	1		_aMarshall, Christopher B
700	1		_aHo, Jason
700	1		_aIshiyama, Noboru
700	1		_aStambolic, Vuk
700	1		_aIkura, Mitsuhiko
773	0		_tThe Journal of biological chemistry _gvol. 289 _gno. 18 _gp. 12195-201
856	4	0	_uhttps://doi.org/10.1074/jbc.C113.543736 _zAvailable from publisher's website
999			_c23657632 _d23657632